We present a report on children with severe pulmonary hypertension secondary to congenital heart disease who received 6 months of beraprost therapy. The children had an increase in intracardiac left-to-right shunt and a reduction of the pulmonary-to-systemic vascular resistance ratio, whereas the pulmonary artery pressure was not significantly changed.
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We thank the cardiac catheterization laboratory staff at Ramathibodi Hospital for facilitating the study and the Ramathibodi metabolic ward staff for assisting with patient care. This work was supported by grants from the Cardiac Children Foundation of Thailand.
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Limsuwan, A., Pienvichit, P. & Khowsathit, P. Beraprost Therapy in Children with Pulmonary Hypertension Secondary to Congenital Heart Disease. Pediatr Cardiol 26, 787–791 (2005). https://doi.org/10.1007/s00246-005-0925-4
- Pulmonary hypertension
- Congenital heart disease
- Eisenmenger syndrome