Abstract
Antifungal properties were introduced in nonwoven regenerated cellulose (RC) nanofibrous membrane using Quillaja saponin. To generate cellulose membranes, deacetylation of electrospun cellulose acetate (CA) nanofibrous membranes was performed using 0.05 M NaOH and ethanol for membranes both loaded and unloaded with Quillaja saponin. Chemical and physical properties of nonwoven CA and RC nanofibrous membrane were characterized using scanning electron microscopy, attenuated total reflectance–Fourier transform infrared spectroscopy, differential scanning calorimetry, and tensile properties. Our results showed that saponin doping did not affect the morphology of the resulting fibers and that the membrane structure was maintained during deacetylation. The antifungal properties of saponin-loaded fabric were determined at 0 and 24 h against two household fungi, Penicillium roguefortii and Aspergillus ochraceus, and compared with control samples. Our findings show that after 24 h the saponin-loaded fabrics had spores kill of 80.4% and 53.6% for P. roguefortii and A. ochraceus, respectively. Fabric containing Quillaja saponin has potential for household applications and could be evaluated further for medical applications.
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Acknowledgments
Funding was provided the National Textile Center United States (Project No. C05-CR01); Intelligent Textile System Research Center at Seoul National University; and Cornell University Agricultural Experiment Station federal formula funds, Project No. NYC-329407, from Cooperative State Research, Education, and Extension Service, United States Department of Agriculture. Thanks also are extended to Yong Joo and Margaret Frey for use of the electrospinning equipment. Ana Leticia Ferreira Bertolo, from the Department of Plant Biology at Cornell University, is highly acknowledged for assistance with the fungus experiment. This work was also supported by the Cornell Center for Materials Research, a Materials Research Science and Engineering Center of the National Science Foundation (Grant No. DMR-0520404).
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Dixit, V., Tewari, J. & Obendorf, S.K. Fungal Growth Inhibition of Regenerated Cellulose Nanofibrous Membranes Containing Quillaja Saponin. Arch Environ Contam Toxicol 59, 417–423 (2010). https://doi.org/10.1007/s00244-010-9493-6
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DOI: https://doi.org/10.1007/s00244-010-9493-6