Abstract
The aim of this study is to evaluate the incidence and clinical features of acute kidney injury (AKI) secondary to ureteral calculi. Between February 2002 and December 2009, the prevalence of AKI was 0.72% in our series of 2,073 cases of ureteral stones. The AKI patients received ureteroscopy or percutaneous nephrostomy as the primary treatment. The most popular symptom was significant decrease in urine output (75%, 12/16). Five cases (33.3%) were caused by bilateral ureteral stones, and 76.19% of the stones were located in the upper ureter, the mean size of single stone was 1.35 ± 0.38 cm. The serum creatinine before treatment was 514.34 ± 267.04 μmol/L and the blood urea nitrogen before treatment was 21.31 ± 10.24 mmol/L. 46.67% of the patients had a functional or anatomical solitary kidney unit. Our study suggests that risk factors for developing AKI in ureteral stone patients are bigger sized stones, ureteral stones in patients with only one functioning kidney or pre-existing kidney disease, and bilateral ureteral stones. Early effective drainage in these cases could decrease the risk developing AKI secondary to ureteral calculi.
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Rabbani MA, Habib HB, Siddiqui BK, Tahir MH, Ahmad B, Murtaza G, Maria Q, Ahmad A (2008) Etiology of acute renal failure in a tertiary center. Saudi J Kidney Dis Transplant 19(6):1009–1014
Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A (2007) Acute kidney injury network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 11(2):R31. doi:10.1186/cc5713
Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P (2004) Acute renal failure—definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 8(4):R204–R212. doi:10.1186/cc2872
Nally JV Jr (2002) Acute renal failure in hospitalized patients. Clevel Clin J Med 69(7):569–574
Dubovsky EV, Russell CD (1982) Quantitation of renal function with glomerular and tubular agents. Semin Nucl Med 12(4):308–329
Herget-Rosenthal S, Marggraf G, Husing J, Goring F, Pietruck F, Janssen O, Philipp T, Kribben A (2004) Early detection of acute renal failure by serum cystatin C. Kidney Int 66(3):1115–1122
Mishra J, Ma Q, Prada A, Mitsnefes M, Zahedi K, Yang J, Barasch J, Devarajan P (2003) Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol 14(10):2534–2543
Mazul-Sunko B, Zarkovic N, Vrkic N, Antoljak N, Bekavac Beslin M, Nikolic Heitzler V, Siranovic M, Krizmanic-Dekanic A, Klinger R (2004) Proatrial natriuretic peptide (1-98), but not cystatin c, is predictive for occurrence of acute renal insufficiency in critically ill septic patients. Nephron Clin Pract 97(3):c103–c107
Perrone RD, Madias NE, Levey AS (1992) Serum creatinine as an index of renal function: new insights into old concepts. Clin Chem 38(10):1933–1953
Andreev E, Koopman M, Arisz L (1999) A rise in plasma creatinine that is not a sign of renal failure: which drugs can be responsible? J Intern Med 246(3):247–252
van Acker BA, Koomen GC, Koopman MG, de Waart DR, Arisz L (1992) Creatinine clearance during cimetidine administration for measurement of glomerular filtration rate. Lancet 340(8831):1326–1329
Mataloun SE, Machado FR, Senna AP, Guimaraes HP, Amaral JL (2006) Incidence, risk factors and prognostic factors of acute renal failure in patients admitted to an intensive care unit. Braz J Med Biol Res 39(10):1339–1347
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Wang, Sj., Mu, Xn., Zhang, Ly. et al. The incidence and clinical features of acute kidney injury secondary to ureteral calculi. Urol Res 40, 345–348 (2012). https://doi.org/10.1007/s00240-011-0414-6
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DOI: https://doi.org/10.1007/s00240-011-0414-6