Urological Research

, Volume 33, Issue 4, pp 247–253

Bone mineral content in calcium renal stone formers

Invited Review


Idiopathic renal calcium stone disease often presents with reduced bone mineral content. Investigations using non-invasive methods for the measurement of bone mineral content (single and dual-photon absorptiometry, dual-energy x-ray absorptiometry, quantitative computed tomodensitometry) show a slight decrease in skeletal mineral content of idiopathic renal stone formers (RSFs).The alterations in bone mineral content in RSFs have different explanations: prostaglandin-mediated bone resorption, subtle metabolic acidosis and 1–25 vitamin D disorders. Bone mineral content is worsened by insufficient dietary calcium leading to a negative calcium balance.


Calcium stone disease Bone mineral density Hypercalciuria Dietary calcium Hyperparathyroidism 


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© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Urology UnitOspedale A. Manzoni

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