Journal of Molecular Evolution

, Volume 86, Issue 3–4, pp 167–171 | Cite as

Primitive Dark-Phase Cycle of Photosynthesis at the Origin of Life

  • Michel Koenig
Letter to the Editor


Simple phosphorylation, isomerization, and aldolisation reactions starting from glyceraldehyde have the potential to lead to the synthesis of pre-ribonucleotide polymers through a primitive form of the Calvin cycle (dark phase of photosynthesis) involving the unusual formation of phospho-nonulose phosphate and phospho-deculose phosphate, as key intermediates. These reactions involve activated phosphates which are generated from schreibersite minerals, geochemically available in Hadean times.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Laboratoire de Génétique de Maladies Rares EA7402, Institut Universitaire de Recherche CliniqueUniversité de MontpellierMontpellierFrance
  2. 2.Laboratoire de Génétique MoléculaireInstitut Universitaire de Recherche Clinique, Centre Hospitalier Universitaire de MontpellierMontpellier Cedex 5France

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