European Journal of Plastic Surgery

, Volume 42, Issue 2, pp 161–168 | Cite as

Pilot study for permanent resolution of axillary hyperhidrosis: elimination of sweat glands with intradermal microneedle radiofrequency

  • Fabian Perez Rivera
Original Paper



Hyperhidrosis is a disorder of the autonomic nervous system that creates severe social and work problems through the production of excess uncontrolled perspiration. This disease affects about 1 to 3% of the world’s population. Essential or primary hyperhidrosis being most frequently seen. Treatment with a variety of surgical and non-surgical systems has been reported. Recently, intradermal microneedle radiofrequency has attracted favorable attention.


Seventy-four armpits in 37 patients (9 males, 28 females, average age 28 years [range 15–68 years]) diagnosed as having axillary hyperhidrosis who were performed intradermal microneedling fractional radiofrequency (MRF) in three deeps 2 mm, 3 mm, and 3.5 mm. The study was performed from July 2014 until July 2016. All patients completed control and follow-up sessions for 6 months.


A permanent decrease in sweating of over 50% was achieved in 30 patients (80%); intermediate results in 2 (7%) and little or no results in 5 patients (13% of patients).


results suggest that MFR is a novel, safe, effective, permanent, and minimally invasive method to treat AHH with tolerable side effects.

Level of Evidence: Level IV, therapeutic study.


Microneedle fractional radiofrequency Thermoregulation Primary hyperhidrosis Joule heating 


Compliance with ethical standards

Conflict of interest

Fabian Perez Rivera declares that he has no conflict of interest.

Ethical approval

For this retrospective study formal consent from a local ethics committee  is not required.

Informed consent

All patients sign two different consents in which they accept to share their photos and information of the treatment for scientific purposes.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Fabian Perez Rivera
    • 1
  1. 1.Buenos AiresArgentina

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