Abstract
Nerve regeneration after an end-to-side neurorrhaphy had been well established in the literature. Both sensory and motor functions could be achieved using this technique. Autonomic and special sensory restoration (e.g., smell sensation) were not studied extensively before. Post-traumatic anosmia has an overall prevalence rate of 7%, with a variable rate of recovery. In this preliminary report, olfactory sensation was restored in a case with a long-standing anosmia using end-to-side nerve graft. The patient reported regaining of smell, which was confirmed by a smell identification test. This technique has the potential to be a promising method for smell restoration; however, it needs further workup and investigations.
Level of Evidence: Level V, therapeutic study.
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Viterbo F, Trindade JC, Hoshino K, Mazzoni A (1992) Latero-terminal neurorrhaphy without removal of the epineural sheath: an experimental study in rats. São Paulo Med J 110:267–275
Geo W, Liu Q, Li S, Zhang J, Li Y (2015) End-to-side neurorrhaphy for nerve repair and functional rehabilitation. J Surg Res 197:427–435
Schriever VA, Merkonidis C, Gupta N, Hummel C, Hummel T (2012) Treatment of smell loss with systemic methylprednisolone. Rhinology 50(3):284–289
Ribas ES, Duffau H (2012) Permanent anosmia and ageusia after resection of a left temporoinsular low-grade glioma: anatomofunctional considerations. J Neurosurg 116(5):1007–1013
Jimenez DF, Sundrani S, Barone CM (1997) Posttraumatic anosmia in craniofacial trauma. J Craniomaxillofac Trauma 3(1):8–15
Lafreniere D, Mann N (2009) Anosmia: loss of smell in the elderly. Otolaryngol Clin North Am 42(1):123–131
Ikeda K, Sakurada T, Takasaka T, Okitsu T, Yoshida S (1995) Anosmia following head trauma: preliminary study of steroid treatment. Tohoku J Exp Med 177(4):343–351
Viterbo F, Amr AH, Stipp EJ, Reis FJ (2009) End-to-side neurorrhaphy: past, present, and future. Plast Reconstr Surg 124(6 Suppl):e351–e358
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Fausto Viterbo, Ahmed M. Gad, and Ryane S. Brock declare that they have no conflict of interest.
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Viterbo, F., Gad, A.M. & Brock, R.S. Neurotization of nasal mucosa by end-to-side nerve graft: preliminary report of smell restoration. Eur J Plast Surg 41, 719–720 (2018). https://doi.org/10.1007/s00238-018-1426-z
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DOI: https://doi.org/10.1007/s00238-018-1426-z