Skip to main content

Advertisement

Log in

The role of dermal regeneration template “Integra®” in reconstructive skin cancer surgery

  • Original Paper
  • Published:
European Journal of Plastic Surgery Aims and scope Submit manuscript

Abstract

Background

Dermal regeneration templates (DRT) use, like “Integra®”, has spread over the past years since its introduction a few decades ago beyond its initial role in burn reconstruction. There is now evidence that it can be used as a biological template in post-cancer excision surgery as a method of reconstructing challenging defects

Methods

We identified the patients that have undergone reconstruction following cutaneous cancer surgery within our institute by reviewing our records. The case notes of the patients were retrieved and the information extracted from the case notes. This is a retrospective analysis of the case studies.

Results

Over the time period of the study, we performed reconstruction using DRT on five individual cases. All the patients did not have any significant post operative complications and the reconstruction seemed durable and reliable. We discuss its benefits as part of the reconstructive ladder post cancer resection reconstructive surgery.

Conclusions

DRT can now play a role in post cancer excision reconstruction in selected patient groups, especially the elderly or in those in which flap reconstruction options have been exhausted or deemed unsuitable.

Level of Evidence: Level V, therapeutic study.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Burke JF, Yannas IV, Quinby WC et al (1981) Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury. Ann Surg 194:413–428

    Article  PubMed  CAS  Google Scholar 

  2. Heimback D, Luterman A, Burke J et al (1988) Artificial dermis for major burns, a multicenter randomized clinical trial. Ann Surg 208:313–320

    Article  Google Scholar 

  3. Frame JD, Still J, Lakhel-LeCaodou A et al (2004) Use of dermal regeneration template in contracture release procedures: a multicenter evaluation. Plast Reconstr Surg 113:1330–1338

    Article  PubMed  Google Scholar 

  4. Tufaro AP, Buck DW 2nd, Fischer AC (2007) The use of artificial dermis in the reconstruction of oncologic surgical defects. Plast Reconstr Surg 120:638–646

    Article  PubMed  CAS  Google Scholar 

  5. Gonyon DL Jr, Zenn MR (2003) Simple approach to the radiated scalp wound using Integra skin substitute. Ann Plast Surg 50:315–320

    Article  PubMed  Google Scholar 

  6. Komorowska-Timek EGA, Bennett DC, Miles D et al (2005) Artificial dermis as an alternative for coverage of complex scalp defects following excision of malignant tumours. Plast Reconstr Surg 115:1010–1017

    Article  PubMed  CAS  Google Scholar 

  7. Van Holder C, Ortiz Carillo S, Malevez C, Jacobs F, Lasudry J (2006) Reconstruction of a fulminant necrotizing fasciitis of the face and neck with a dermal regeneration template. Eur J Plast Surg 29(3):147–150

    Article  Google Scholar 

  8. Chalmers RL, Smock E, Geh JLC (2010) Experience of Integra(®) in cancer reconstructive surgery. J Plast Reconstr Aesthet Surg 62(12):2081–2090

    Article  Google Scholar 

  9. Dantzer E, Braye FM (2001) Reconstructive surgery using an artificial dermis (Integra): results with 39 grafts. Br J Plast Surg 54:659–664

    Article  PubMed  CAS  Google Scholar 

  10. Ghattaura A, Potokar TS (2009) Calcified Integra membrane: one possible cause of skin graft failure in the second stage of Integra use. Eur J Plast Surg 32(1):47–50

    Article  Google Scholar 

Download references

Conflict of Interest

None

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ali Souéid.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Souéid, A., El-Tigani, ET. The role of dermal regeneration template “Integra®” in reconstructive skin cancer surgery. Eur J Plast Surg 36, 247–250 (2013). https://doi.org/10.1007/s00238-012-0753-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00238-012-0753-8

Keywords

Navigation