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One-stage prefabrication for composite tissue defects including two different tissue layers using high-density porous polyethylene and acellular dermal matrix

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Abstract

Functional and three-dimensional reconstruction of lost or deformed body parts is the main aim of plastic surgery. Many techniques can and have been used for this purpose. Prefabrication can be used to reduce donor site morbidity. Although prefabrication reduces donor site morbidity, it usually requires multistage operations especially for composite defects. We report the prefabrication of two different implants in one stage using high-density porous polyethylene and acellular dermal matrix in rats, since these materials do not require an immediate blood supply. Before surgery, a high-density porous polyethylene layer and a 2 × 1cm acellular dermal matrix were prepared and sutured to each other. The femoral artery, vein, and nerve were used as a pedicle. The pedicle was placed and anchored underneath the implants; in order to prevent neovascularization from another source, this complex was wrapped in a silicone sheet. A total of ten implants were prefabricated. Six weeks after the surgery, the implants were evaluated macroscopically and histologically. Macroscopic and histological examinations showed that two different implants could be prefabricated in one stage for composite defects.

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Authors and Affiliations

  1. Plastic, Reconstructive and Aesthetic Surgery, Ankara University Faculty of Medicine, Ankara, 06590, Turkey

    Savaş Serel, Arsın Uluç, Burak Kaya & Hakan Gence

  2. Department of Pathology, Ankara University Faculty of Medicine, Ankara, 06590, Turkey

    Aylin Okçu Heper

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  1. Savaş Serel
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  2. Arsın Uluç
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  3. Burak Kaya
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  4. Hakan Gence
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  5. Aylin Okçu Heper
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Correspondence to Savaş Serel.

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Serel, S., Uluç, A., Kaya, B. et al. One-stage prefabrication for composite tissue defects including two different tissue layers using high-density porous polyethylene and acellular dermal matrix. Eur J Plast Surg 31, 315–319 (2008). https://doi.org/10.1007/s00238-008-0275-6

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  • DOI: https://doi.org/10.1007/s00238-008-0275-6

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