Skip to main content

Advertisement

Log in

Therapy resistant traumatic fungal infection necessitating arm amputation after free flap coverage

  • Case Report
  • Published:
European Journal of Plastic Surgery Aims and scope Submit manuscript

Abstract

The indication for microvascular free tissue transfer is usually exposure of vital structures, bone defect, or loss of function. Radical debridement and control of infection is a prerequisite for any kind of reconstructive procedure. This is especially true for untidy wounds in industrial or agricultural settings; in these, one should not hesitate to debride any tissue which is not obviously viable. Aggressive surgical debridement should be performed before flap coverage. Some organisms, however, fail to be eradicated by mechanical debridement as they are particularly pathogenic or embedded in the tissues. Perforator flaps are currently recommended for soft tissue coverage of the upper limb, for their pliability and the low morbidity of the donor site. A case of traumatic deglovement injury of an upper arm is presented. After free flap coverage, it was complicated by a rare and highly pathogenic fungal infection. Successful soft tissue reconstruction obtained with a chimeric free flap was compromised by an expanding fungal infection ultimately leading to limb amputation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

References

  1. Calderon W, Chang N, Mathes SJ (1986) Comparison of the effect of bacterial inoculation in muscolocutaneous and fasciocutaneous flaps. Plast Reconstr Surg 77:785–794

    Article  PubMed  CAS  Google Scholar 

  2. Clark FL, Batra RS, Gladstone HB (2003) Mohs micrographic surgery is an alternative treatment method for cutaneous mucormycosis. Dermatol Surg 29:882–885

    Article  PubMed  Google Scholar 

  3. Derderian CA, Olivier WA, Baux G, Levine J, Gurtner GC (2003) Microvascular free-tissue transfer for traumatic defects of the upper extremity: a 25-year experience. J Reconstr Microsurg 19(7):455–462

    Article  PubMed  Google Scholar 

  4. Eucker J, Sezer O, Graf B, Possinger K (2001) Mucormycoses. Mycoses 44:253–260

    Article  PubMed  CAS  Google Scholar 

  5. Hallock GG (1991) Complication of 100 consecutive local fasciocutaneous flaps. Plast Reconstr Surg 88:264–268

    Article  PubMed  CAS  Google Scholar 

  6. Hamdi M, Van Landuyt K, Blondeel P, Monstrey S (2004) Aesthetic and functional consideration in the reconstruction of large skin defects with free flaps. Clin Plast Surg 31:39–48

    Article  PubMed  Google Scholar 

  7. Hamdi M, Van Landuyt K, Monstrey S, Blondeel P (2004) A clinical experience with perforator flaps in the coverage of extensive defects of the upper extremity. Plast Reconstr Surg 113(4):1175–1183

    Article  PubMed  Google Scholar 

  8. Harii K, Torii S, Sekiguchi J (1978) The free lateral thoracic flap. Plast Reconstr Surg 62:212–222

    Article  PubMed  CAS  Google Scholar 

  9. Losee JE, Selber J, Vega S, Hall C, Scott G, Serletti JM (2002) Primary cutaneous Mucormycosis: guide to surgical management. Ann Plast Surg 49(4):385–390

    Article  PubMed  Google Scholar 

  10. Pederson CW (2001) Upper extremity microsurgery. Plast Reconstr Surg 107:1524–1536

    Article  PubMed  CAS  Google Scholar 

  11. Sun QN, Najvar LK, Bocanegra R, Loebenberg D, Graybill JR (2002) In vivo activity of Posaconazole against Mucor spp. in an immunosuppressed-mouse model. AAC 46:2310–2312

    CAS  Google Scholar 

  12. Verma GR, Lobo DR, Walker R, Bose SM, Gupta KL (1995) Disseminated mucormycosis in healthy adults. J Postgrad Med 41(2):40–42

    PubMed  CAS  Google Scholar 

  13. Welsch MJ, Moon CM, Elston DM, Vogel P (2003) Invasive synergistic fungal infection after motor vehicle collision. Cutis 71:201–204

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. Dall’Antonia.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dall’Antonia, A., Hamdi, M., Van Landuyt, K. et al. Therapy resistant traumatic fungal infection necessitating arm amputation after free flap coverage. Eur J Plast Surg 31, 187–191 (2008). https://doi.org/10.1007/s00238-008-0235-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00238-008-0235-1

Keywords

Navigation