European Journal of Plastic Surgery

, Volume 28, Issue 6, pp 385–388 | Cite as

Recurrence rate of giant cell tumors of the tendon sheath

  • H. Lowyck
  • L. De SmetEmail author
Original Paper


Recurrence of giant cell tumors of the tendon sheath in the hand has continued to be a problem since it was first described. Authors have tried to identify factors to predict the chance of recurrence and have found several. This paper reports our experience with resection of GCTTS in the hand, and the predisposing factors of recurrence were studied. The recurrence rate of 16% is similar to that of earlier published results. The predisposing factors for recurrence such as pressure erosion on X-ray and presence of degenerative changes could not be confirmed.


Tumor Tendon sheath Soft tissue Giant cell Nodular tenosynovitis 


  1. 1.
    Al-Qattan M (2001) Giant cell tumours of tendon sheath: classification and recurrence rate. Br J Hand Surg 26B:72–75CrossRefGoogle Scholar
  2. 2.
    Chaissaignac EDM (1852) Cancer de la gaines des tendons. Gaz Hospitaux Militaires 47:185–186Google Scholar
  3. 3.
    Dal Cin P et al (1994) Cytogenetic characterization of tenosynovial giant cell tumors (nodular tenosynovits). Cancer Res 54:3986–3987Google Scholar
  4. 4.
    Dal Cin P et al (1996) A new cytogenetic subgroup in tenosynovial giant cell tumors (nodular tenosynovitis) is characterized by involvement of 16q24. Cancer Genet Cytogenet 87:85–87CrossRefPubMedGoogle Scholar
  5. 5.
    Fyfe IS et al (1980) Pigmented villo-nodular synovitis of the hand. Hand 12:179–188PubMedGoogle Scholar
  6. 6.
    Glowacki K (1995) Giant cell tumors of tendon sheath. Hand Clin 2:245–253Google Scholar
  7. 7.
    Granowitz SP, et al (1976) The pathogenesis and long term end results of pigmented villonodular synovitis. Clin Orthop 114:335–351PubMedGoogle Scholar
  8. 8.
    Grover R, Grobbelaar A, Richman P, Smith T (1998) Measurement of an invasive potential provides an accurate prognostic marker for giant cell tumor of tendon sheath. J Hand Surg 27B:728–734Google Scholar
  9. 9.
    Jones FE, et al (1969) Fibrous xanthoma of the synovium (giant-cell tumor of tendon sheath, pigmented nodular synovitis): a study of one hundred and eighteen cases. J Bone Joint Surg 51A:76–86Google Scholar
  10. 10.
    Lorea P, Van De Walle H, Kinnen L, Ledoux P, Meermans JP, Van Den Heule B (2004) Giant cell tumours of tendon sheath: lack of correlation between NM23-H1 expression and recurrence. J Hand Surg 29B:67–70Google Scholar
  11. 11.
    Martens M, et al (1972) Pigmented villonodular synovitis of joints, tendons and bursae. Acta Orthop Belg 38:233–255PubMedGoogle Scholar
  12. 12.
    Masahiro, et al (1986) Giant cell tumor of the tendon sheath (nodular tenosynovitis). A study of 207 cases to compare large joint group with the common digit group. Cancer 57:875–884PubMedGoogle Scholar
  13. 13.
    Monaghan H, et al (2001) Giant cell tumour of the tendon sheath (localised nodular tenosynovitis): clinicopathological features of 71 cases. J Clin Pathol 54:404–407CrossRefPubMedGoogle Scholar
  14. 14.
    Moore JR, et al (1984) Localised nodular tenosynovitis: experience with 115 cases. J Hand Surg 9A:412–417Google Scholar
  15. 15.
    Prakash P, Kotwal, et al (2000) Giant-cell tumour of the tendon sheath: is radiotherapy indicated to prevent recurrence after surgery? Br J Bone Joint Surg 82B:571–573Google Scholar
  16. 16.
    Rao AS, Vigorita VJ (1984) Pigmented villonodular synovitis (giant cell tumour of tendon sheath and synovial membrane): a review of 81 cases. J Bone Joint Surg Am 66:76–94PubMedGoogle Scholar
  17. 17.
    Reilly K, et al (1999) Recurrent giant cell tumors of the tendon sheath. J Hand Surg Am 24A:1298–1302CrossRefGoogle Scholar
  18. 18.
    Rodrigues C, et al (1998) Giant cell tumor of the tendon sheath: a retrospective study of 28 cases. J Surg Oncol 68:100–103CrossRefPubMedGoogle Scholar
  19. 19.
    Shultz RJ, et al (1983) Tumors in the hand. J Hand Surg 8:803–808Google Scholar
  20. 20.
    Wright CJE (1951) Benign giant cell synovioma: an investigation of 85 cases. Br J Surg 38:257–271PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Department of Orthopedic SurgeryU.Z. PellenbergBelgium

Personalised recommendations