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Intracranial leiomyosarcoma in a patient with AIDS

  • DIAGNOSTIC NEURORADIOLOGY
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Abstract

We report an intracranial leiomyosarcoma in the pontine cistern of a 34-year-old woman infected with the human immunodeficiency virus (HIV). The clinical, radiological and pathological data are reviewed. The tumor was Epstein-Barr virus (EBV) positive by in situ hybridization. This case emphasizes that smooth muscle neoplasms arising in the setting of immunocompromise can occur intracranially, and corroborates a hypothesis that EBV coinfection may have a role in development of these tumors.

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Authors and Affiliations

  1. Department of Pathology, Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21287, USA, , , , , , TP

    H. G. Brown & P. C. Burger

  2. Department of Neurosurgery, Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21287, USA, , , , , , TP

    A. Olivi & A. K. Sills

  3. Department of Medicine, Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21287, USA, , , , , , TP

    P. A. Barditch-Crovo

  4. Department of Radiology, Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21287, USA, , , , , , TP

    R. R. Lee

Authors
  1. H. G. Brown
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  2. P. C. Burger
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  3. A. Olivi
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  4. A. K. Sills
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  5. P. A. Barditch-Crovo
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  6. R. R. Lee
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Additional information

Received: 5 May 1998 Accepted: 18 May 1998

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Brown, H., Burger, P., Olivi, A. et al. Intracranial leiomyosarcoma in a patient with AIDS. Neuroradiology 41, 35–39 (1999). https://doi.org/10.1007/s002340050701

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  • DOI: https://doi.org/10.1007/s002340050701

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