Abstract
Hypermanganesaemia is reported in patients on long-term parenteral nutrition. Deposition of manganese, giving high signal on T1-weighted images, may involve the basal ganglia. MRI in nine patients (mean age 51 years, range 31–75 years) on long-term parenteral nutrition (mean duration 30 months, range 6–126 months), demonstrated high signal in the anterior pituitary gland on T1-weighted sagittal and coronal images. The gland appeared normal on T2-weighted images. Signal intensity in the basal ganglia on T1-weighted images was increased in all patients. Endocrine assessment showed no significant abnormality. Neurological examination showed a mild parkinsonian movement disorder in one patient. Hypermanganaesemia was present in all nine (1.3–2.8 μmol/l, mean 1.87 μmol/l). The high signal in the anterior pituitary gland was probably related to deposition of paramagnetic substances, especially manganese.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 20 January 1998 Accepted: 10 April 1998
Rights and permissions
About this article
Cite this article
Dietemann, J., Reimund, J., Diniz, R. et al. High signal in the adenohypophysis on T1-weighted images presumably due to manganese deposits in patients on long-term parenteral nutrition. Neuroradiology 40, 793–796 (1998). https://doi.org/10.1007/s002340050686
Issue Date:
DOI: https://doi.org/10.1007/s002340050686