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Neuroradiology

, Volume 54, Issue 7, pp 691–697 | Cite as

Predictability of motor outcome according to the time of diffusion tensor imaging in patients with cerebral infarct

  • Yong Hyun Kwon
  • Yong Jae Jeoung
  • Jun Lee
  • Su Min Son
  • Saeyoon Kim
  • Chulseung Kim
  • Sung Ho JangEmail author
Diagnostic Neuroradiology

Abstract

Introduction

Predictability of diffusion tensor imaging tractography (DTT) for motor outcome can differ according to the time of DTT. We attempted to compare the predictability for motor outcome according to the time of diffusion tensor imaging (DTI) by analyzing the corticospinal tract (CST) integrity on DTT in patients with corona radiata (CR) infarct.

Methods

Seventy-one consecutive hemiparetic patients with CR infarct were recruited. Motor function of the affected extremities was measured twice: at onset and at 6 months from onset. According to the time of DTI, patients were classified into two groups: the early scanning group (ES group) within 14 days since stroke onset; and the late scanning group (LS group) 15–28 days. Motor outcome was compared with the CST integrity on DTT.

Results

Motor prognosis was predicted from scan time of DTI and the CST integrity on DTT in the logistic regression model. According to separate regression analysis, the CST integrity of the late group was found to predict MI score (OR = 14.000, 95% CI = 3.194–61.362, p < 0.05), whereas the CST integrity of the early group was not found to predict MI score.

Conclusions

In terms of both positive and negative predictabilities, we found that predictability of DTT for motor outcome was better in patients who were scanned later (15–28 days after onset) than in patients who were scanned earlier (1–14 days after onset).

Keywords

Diffusion tensor imaging Motor function Prognosis Stroke Corona radiata 

Notes

Acknowledgments

This work was supported by National Research Foundation of Korea Grant funded by the Korean Government (KRF-2008-314-E00173).

Conflict of interest

We declare that we have no conflict of interest.

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Yong Hyun Kwon
    • 1
  • Yong Jae Jeoung
    • 2
  • Jun Lee
    • 3
  • Su Min Son
    • 4
  • Saeyoon Kim
    • 5
  • Chulseung Kim
    • 6
  • Sung Ho Jang
    • 4
    Email author
  1. 1.Department of Physical TherapyYeungnam College of Science and TechnologyTaeguRepublic of Korea
  2. 2.Department of Physical Medicine and Rehabilitation, College of MedicineYeungnam UniversityTaeguRepublic of Korea
  3. 3.Department of Neurology, College of MedicineYeungnam UniversityTaeguRepublic of Korea
  4. 4.Department of Physical Medicine and Rehabilitation, College of MedicineYeungnam University 317-1TaeguRepublic of Korea
  5. 5.Department of Pediatrics, College of MedicineYeungnam UniversityTaeguRepublic of Korea
  6. 6.Medical Devices Clinical Trial Center of Yeungnam University HospitalTaeguRepublic of Korea

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