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Preoperative subtyping of meningiomas by perfusion MR imaging

  • Diagnostic Neuroradiology
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Abstract

Introduction

This paper aims to evaluate the value of perfusion magnetic resonance (MR) imaging in the preoperative subtyping of meningiomas by analyzing the relative cerebral blood volume (rCBV) of three benign subtypes and anaplastic meningiomas separately.

Materials and methods

Thirty-seven meningiomas with peritumoral edema (15 meningothelial, ten fibrous, four angiomatous, and eight anaplastic) underwent perfusion MR imaging by using a gradient echo echo-planar sequence. The maximal rCBV (compared with contralateral normal white matter) in both tumoral parenchyma and peritumoral edema of each tumor was measured. The mean rCBVs of each two histological subtypes were compared using one-way analysis of variance and least significant difference tests. A p value less than 0.05 indicated a statistically significant difference.

Results

The mean rCBV of meningothelial, fibrous, angiomatous, and anaplastic meningiomas in tumoral parenchyma were 6.93 ± 3.75, 5.61 ± 4.03, 11.86 ± 1.93, and 5.89 ± 3.85, respectively, and in the peritumoral edema 0.87 ± 0.62, 1.38 ± 1.44, 0.87 ± 0.30, and 3.28 ± 1.39, respectively. The mean rCBV in tumoral parenchyma of angiomatous meningiomas and in the peritumoral edema of anaplastic meningiomas were statistically different (p < 0.05) from the other types of meningiomas.

Conclusion

Perfusion MR imaging can provide useful functional information on meningiomas and help in the preoperative diagnosis of some subtypes of meningiomas.

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Acknowledgment

We thank Stella Noach (Department of radiology, University Medical Center Groningen) for her grammatical correction of our paper.

Conflict of interest statement

We declare that we have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

    Hao Zhang, Lars A. Rödiger & Matthijs Oudkerk

  2. Department of Radiology, Shanghai Jiaotong University affiliated First People’s Hospital, Shanghai, 200080, China

    Hao Zhang & Jingtao Miao

  3. Department of Radiology, Fudan University Huashan Hospital, Shanghai, 200050, China

    Tianzhen Shen

Authors
  1. Hao Zhang
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  2. Lars A. Rödiger
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  3. Tianzhen Shen
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  4. Jingtao Miao
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  5. Matthijs Oudkerk
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Correspondence to Hao Zhang.

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Zhang, H., Rödiger, L.A., Shen, T. et al. Preoperative subtyping of meningiomas by perfusion MR imaging. Neuroradiology 50, 835–840 (2008). https://doi.org/10.1007/s00234-008-0417-3

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  • DOI: https://doi.org/10.1007/s00234-008-0417-3

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