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Differential diagnosis of mesiotemporal lesions: case report of neurosyphilis


We report a clinical and imaging case of suspected herpes simplex encephalitis subsequently diagnosed as neurosyphilis based on positive antibodies in the CSF. MRI of the brain showed cortical and subcortical lesions in the mesial temporal region, septal area, insula and cingulated gyrus of the right cerebral hemisphere. Neurosyphilis should be included in the differential diagnosis of mesial temporal region lesions on MRI.

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Correspondence to A. Vieira Santos.

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Vieira Santos, A., Matias, S., Saraiva, P. et al. Differential diagnosis of mesiotemporal lesions: case report of neurosyphilis. Neuroradiology 47, 664–667 (2005).

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  • Neurosyphilis
  • Mesial temporal lesions
  • MRI