Diffusion tensor imaging of the brain: review of clinical applications

Abstract

We review the theoretical background to diffusion tensor imaging (DTI) and some of its commoner clinical applications, such as cerebral ischemia, brain maturation and traumatic brain injury. We also review its potential use in diseases such as epilepsy, multiple sclerosis, and Alzheimer’s disease. The value of DTI in the investigation of brain tumors and metabolic disorders is assessed.

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Acknowledgements

We wish to say a special thank you to Professor Thomas Chenevert, Department of Radiology, University of Michigan Hospitals, for valuable comments and support in the preparation of this manuscript.

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Correspondence to P. C. Sundgren.

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Sundgren, P.C., Dong, Q., Gómez-Hassan, D. et al. Diffusion tensor imaging of the brain: review of clinical applications. Neuroradiology 46, 339–350 (2004). https://doi.org/10.1007/s00234-003-1114-x

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Keywords

  • Magnetic resonance imaging
  • Diffusion tensor imaging
  • Brain