Skip to main content

Advertisement

Log in

Potential association between chia seeds use and low atazanavir trough concentrations in an HIV-infected patient

  • Correspondence
  • Published:
European Journal of Clinical Pharmacology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Data availability

Data are available from the corresponding author upon reasonable request.

References

  1. Bahall M (2017) Prevalence, patterns, and perceived value of complementary and alternative medicine among HIV patients: a descriptive study. BMC Complement Altern Med 17:422

    Article  PubMed  PubMed Central  Google Scholar 

  2. Halpin SN, Carruth EC, Rai RP, Edelman EJ, Fiellin DA, Gibert C et al (2018) Complementary and alternative medicine among persons living with HIV in the era of combined antiretroviral treatment. AIDS Behav 22:848–852

    Article  PubMed  PubMed Central  Google Scholar 

  3. Brooks KM, George JM, Kumar P (2017) Drug interactions in HIV treatment: complementary & alternative medicines and over-the-counter products. Expert Rev Clin Pharmacol 10:59–79

    Article  CAS  PubMed  Google Scholar 

  4. Jalloh MA, Gregory PJ, Hein D, Risoldi Cochrane Z, Rodriguez A (2017) Dietary supplement interactions with antiretrovirals: a systematic review. Int J STD AIDS 28:4–15

    Article  CAS  PubMed  Google Scholar 

  5. Gervasoni C, Formenti T, Cattaneo D (2019) Management of polypharmacy and drug-drug interactions in HIV patients: a 2-year experience of a multidisciplinary outpatient clinic. AIDS Rev 21:40–49

    Article  PubMed  Google Scholar 

  6. Ekwunife OI, Oreh C, Ubaka CM (2012) Concurrent use of complementary and alternative medicine with antiretroviral therapy reduces adherence to HIV medications. Int J Pharm Pract 20:340–343

    Article  PubMed  Google Scholar 

  7. Bordes C, Leguelinel-Blache G, Lavigne JP, Mauboussin JM, Laureillard D, Faure H et al (2020) Interactions between antiretroviral therapy and complementary and alternative medicine: a narrative review. Clin Microbiol Infect 26:1161–1170

    Article  CAS  PubMed  Google Scholar 

  8. Cattaneo D, Giacomelli A, Gervasoni C (2018) Loss of control of HIV viremia with OTC weight-loss drugs: a call for caution? Obesity (Silver Spring) 26:1251–1252

    Article  PubMed  Google Scholar 

  9. Cattaneo D, Giacomelli A, Gervasoni C (2021) Liver injury after dietary supplements in patients living with HIV: a call to action. Clin Gastroenterol Hepatol S1542–3565

  10. Cordova E, Morganti L, Rodriguez C (2017) Possible drug-herb interaction between herbal supplement containing horsetail (equisetum arvense) and antiretroviral drugs. J Int Assoc Provid AIDS Care 16:11–13

    Article  PubMed  Google Scholar 

  11. Silva LA, Verneque BJF, Mota APL, Duarte CK (2021) Chia seed (Salvia hispanica L.) consumption and lipid profile: a systematic review and meta-analysis. Food Funct 12:8835–8849

  12. da Silva BP, Toledo RCL, Grancieri M, Moreira MEC, Medina NR, Silva RR et al (2019) Effects of chia (Salvia hispanica L.) on calcium bioavailability and inflammation in Wistar rats. Food Res Int 116:592–599

  13. Vazquez-Ovando A, Rosado-Rubio G, Chel-Guerrero L, Betancur D (2009) Physicochemical properties of a fibrous fraction from chia (Salvia hispanica L.). LWT - Food Sci Technol 167–173

  14. Pereira da Silva B, Kolba N, Stampini Duarte Martino H, Hart J, Tako E (2019) Soluble extracts from chia seed (Salvia hispanica L.) affect brush border membrane functionality, morphology and intestinal bacterial populations in vivo (Gallus gallus). Nutrients 11:2457

  15. Tawfik SA, Awad ET, Abu Bakr HO, Ahmed IM, Ashour E, Gamal-Eldeen AM (2023) Chia seeds oil suppresses the resistance of hepatocellular carcinoma cells to liposomal-doxorubicin and upregulates the tumor suppressor miRNAs. Curr Pharm Biotechnol 24:570–578

    Article  CAS  PubMed  Google Scholar 

  16. Cattaneo D, Riva A, Clementi E, Milazzo L, Gervasoni C (2016) Severe hyperbilirubinemia in an HIV-HCV-coinfected patient starting the 3D regimen that resolved after TDM-guided atazanavir dose reduction. Ther Drug Monit 38:285–287

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

DC and CG supervised all the stages of the study and wrote the first draft of the manuscript. VM performed laboratory analyses and revised the draft manuscript. SP, MB took care of the patient and revised the draft manuscript.

Corresponding author

Correspondence to Cristina Gervasoni.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cattaneo, D., Pagano, S., Beltrami, M. et al. Potential association between chia seeds use and low atazanavir trough concentrations in an HIV-infected patient. Eur J Clin Pharmacol 79, 1145–1146 (2023). https://doi.org/10.1007/s00228-023-03524-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00228-023-03524-1

Navigation