Skip to main content

Pharmacokinetics of cefoperazone/sulbactam in plasma and cerebrospinal fluid in patients with intraventricular hemorrhage after external ventricular drains

European Journal of Clinical Pharmacology volume 76, pages 127–129 (2020)Cite this article

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

USD 39.95

Price includes VAT (USA)
Tax calculation will be finalised during checkout.

Fig. 1

References

  1. Dos Santos SC, Fortes Lima TT, Lunardi LW, Stefani MA (2017) External ventricular drain-related infection in spontaneous intracerebral hemorrhage. World Neurosurg 99:580–583

    Article  Google Scholar 

  2. Hagel S, Bruns T, Pletz MW, Engel C, Kalff R, Ewald C (2014) External ventricular drain infections: risk factors and outcome. Interdiscip Perspect Infect Dis 2014:708531

    CAS  Article  Google Scholar 

  3. Peter S, Roman B, Marjan Z (2016) External ventricular drainage infections: a single-centre experience on 100 cases. J Neurol Neurophysiol 7:392

    Article  Google Scholar 

  4. Sam JE, Lim CL, Sharda P, Wahab NA (2018) The organisms and factors affecting outcomes of external ventricular drainage catheter-related ventriculitis: a Penang Experience. Asian J Neurosurg 13:250–257

    Article  Google Scholar 

  5. Yadegarynia D, Gachkar L, Fatemi A, Zali A, Nobari N, Asoodeh M, Parsaieyan Z (2014) Changing pattern of infectious agents in postneurosurgical meningitis. Caspian J Intern Med 5:170–175

    PubMed  PubMed Central  Google Scholar 

  6. Chen BY, He LX, Hu BJ (2012) Consensus of the Chinese specialists for diagnosis, treatment & control of Acinetobacter baumannii infection. Zhonghua Yi Xue Za Zhi 92:76–85

    PubMed  Google Scholar 

  7. Deveci A, Coban AY, Acicbe O, Tanyel E, Yaman G, Durupinar B (2012) In vitro effects of sulbactam combinations with different antibiotic groups against clinical Acinetobacter baumannii isolates. J Chemother 24:247–252

    CAS  Article  Google Scholar 

  8. Chen F, Wang L, Wang M, Xie Y, Xia X, Li X, Liu Y, Cao W, Zhang T, Li P, Yang M (2018) Genetic characterization and in vitro activity of antimicrobial combinations of multidrug-resistant Acinetobacter baumannii from a general hospital in China. Oncol Lett 15:2305–2315

    PubMed  Google Scholar 

  9. Niu T, Luo Q, Li Y, Zhou Y, Yu W, Xiao Y (2019) Comparison of tigecycline or cefoperazone/sulbactam therapy for bloodstream infection due to carbapenem-resistant Acinetobacter baumannii. Antimicrob Resist Infect Control 8:52

    Article  Google Scholar 

  10. Xu H, Kong L, Wu C, Xu B, Wu X (2019) Pharmacokinetics of meropenem in plasma and cerebrospinal fluid in patients with intraventricular hemorrhage after lateral ventricle drainage. Eur J Clin Pharmacol 75:595–597

    CAS  Article  Google Scholar 

  11. Cockcroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16:31–41

    CAS  Article  Google Scholar 

  12. Wang Q, Wu Y, Chen B, Zhou J (2015) Drug concentrations in the serum and cerebrospinal fluid of patients treated with cefoperazone/sulbactam after craniotomy. BMC Anesthesiol 15:33

    CAS  Article  Google Scholar 

Download references

Funding

This study was financially supported by the Research Innovation Program for College Graduates of Bengbu Medical College (Byycx1761 and Byycxz1833) and Natural Science Foundation of Anhui (1708085QH208).

Author information

Author notes

  1. Liang Meng and Lingti Kong contributed equally to this work.

Authors and Affiliations

  1. Department of Emergency Internal Medicine, The First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, China

    Liang Meng, Benquan Qi & Xiaofei Wu

  2. Department of Pharmacy, The First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, China

    Lingti Kong

  3. Department of Endocrinology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, China

    Chenchen Wu

Authors
  1. Liang Meng
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Lingti Kong
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Chenchen Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Benquan Qi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Xiaofei Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Xiaofei Wu.

Ethics declarations

Conflict of interest

The authors declare that they have no conflicts of interests.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Meng, L., Kong, L., Wu, C. et al. Pharmacokinetics of cefoperazone/sulbactam in plasma and cerebrospinal fluid in patients with intraventricular hemorrhage after external ventricular drains. Eur J Clin Pharmacol 76, 127–129 (2020). https://doi.org/10.1007/s00228-019-02773-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00228-019-02773-3