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Meta-analysis on vitamin C and the common cold in children may be misleading

European Journal of Clinical Pharmacology volume 75, pages 1747–1748 (2019)Cite this article

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References

  1. Hemilä H, Chalker E (2013) Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev 1:CD000980. https://doi.org/10.1002/14651858.CD000980.pub4

    Article  Google Scholar 

  2. Vorilhon P, Arpajou B, Vaillant Roussel H, Merlin É, Pereira B, Cabaillot A (2019) Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection: a meta-analysis in children. Eur J Clin Pharmacol 75:303–311. https://doi.org/10.1007/s00228-018-2601-7

    Article  CAS  PubMed  Google Scholar 

  3. Cohen HA, Varsano I, Kahan E, Sarrell EM, Uziel Y (2004) Effectiveness of an herbal preparation containing echinacea, propolis, and vitamin C in preventing respiratory tract infections in children: a randomized, double-blind, placebo-controlled, multicenter study. Arch Pediatr Adolesc Med 158:217–221. https://doi.org/10.1001/archpedi.158.3.217

    Article  PubMed  Google Scholar 

  4. Karsch-Völk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, Linde K (2014) Echinacea for preventing and treating the common cold. Cochrane Database Syst Rev 2:CD000530. https://doi.org/10.1002/14651858.CD000530.pub3

    Article  Google Scholar 

  5. Coulehan JL, Reisinger KS, Rogers KD, Bradley DW (1974) Vitamin C prophylaxis in a boarding school. N Engl J Med 290(1):6–10. https://doi.org/10.1056/NEJM197401032900102

    Article  CAS  PubMed  Google Scholar 

  6. Cochrane Handbook for Systematic Reviews of Interventions [Version 5.1.0; March 2011], sections 8.9.2.2. and 16.1.3.1. http://training.cochrane.org/handbook. Accessed 16 May 2019

  7. Ludvigsson J, Hansson LO, Tibbling G (1977) Vitamin C as a preventive medicine against common colds in children. Scand J Infect Dis 9:91–98. https://www.ncbi.nlm.nih.gov/pubmed/897573

    Article  CAS  PubMed  Google Scholar 

  8. Coulehan JL, Eberhard S, Kapner L, Taylor F, Rogers K, Garry P (1976) Vitamin C and acute illness in Navajo school children. N Engl J Med 295:973–977. https://doi.org/10.1056/NEJM197610282951802

    Article  CAS  PubMed  Google Scholar 

  9. Ritzel G (1961) Critical evaluation of vitamin C as a prophylactic and therapeutic agent in colds [in German]. Helv Med Acta 28:63–68. Translation available at: https://www.mv.helsinki.fi/home/hemila/T3.pdf. Accessed 16 May 2019

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Public Health, University of Helsinki, POB 41, FI-00014, Helsinki, Finland

    Harri Hemilä

  2. University of Sydney, Sydney, Australia

    Elizabeth Chalker

Authors
  1. Harri Hemilä
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  2. Elizabeth Chalker
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Correspondence to Harri Hemilä.

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Hemilä, H., Chalker, E. Meta-analysis on vitamin C and the common cold in children may be misleading. Eur J Clin Pharmacol 75, 1747–1748 (2019). https://doi.org/10.1007/s00228-019-02733-x

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  • DOI: https://doi.org/10.1007/s00228-019-02733-x

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