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Warfarin resistance from primidone in patient with essential tremor

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References

  1. Koller WC, Vetere-Overfield B (1989) Acute and chronic effects of propranolol and primidone in essential tremor. Neurology 39(12):1587–1588. https://doi.org/10.1212/WNL.39.12.1587

    Article  CAS  PubMed  Google Scholar 

  2. Deuschl G, Raethjen J, Hellriegel H, Elble R (2011) Treatment of patients with essential tremor. Lancet Neurol 10(2):148–161. https://doi.org/10.1016/S1474-4422(10)70322-7

    Article  PubMed  Google Scholar 

  3. Wittkowsky AK, Boccuzzi SJ, Wogen J, Wygant G, Patel P, Hauch O (2004) Frequency of concurrent use of warfarin with potentially interacting drugs. Pharmacotherapy 24:1168–1674

    Google Scholar 

  4. Package insert, primidone, Qualitest Pharmaceuticals 2010

  5. Battino D, Avanzini G, Bossi L, Croci D, Cusi C, Gomeni C, Moise A (1983) Plasma levels of primidone and its metabolite phenobarbital: effect of age and associated therapy. Ther Drug Monit 5(1):73–79. https://doi.org/10.1097/00007691-198303000-00006

    Article  CAS  PubMed  Google Scholar 

  6. Chen Y, Ferguson SS, Negishi M, Goldstein JA (2004) Induction of human CYP2C9 by rifampicin, hyperforin and phenobarbital is medicated by pregnane X receptor. J Pharmacol Exp Ther 308(2):495–501. https://doi.org/10.1124/jpet.103.058818

    Article  CAS  PubMed  Google Scholar 

  7. MacDonald MG, Robinson DS, Sylwester D, Jaffe JJ (1969) The effects of phenobarbital, choral betaine, and glutethimide administration on warfarin plasma levels and hypoprothrombinemic responses in man. Clin Pharmacol Ther 10(1):80–84. https://doi.org/10.1002/cpt196910180

    Article  CAS  PubMed  Google Scholar 

  8. Udall JA (1975) Clinical implications of warfarin interactions with five sedatives. Am J Cardiol 35(1):67–71. https://doi.org/10.1016/0002-9149(75)90560-3

    Article  CAS  PubMed  Google Scholar 

  9. Clark NP, Hoang K, Delate T, Horn JR, Witt DM (2017) Warfarin interaction with hepatic cytochrome P-450 enzyme-inducing anticonvulsants. Clin Appl Thromb Hemost Jan 1:1076029616687849. https://doi.org/10.1177/1076029616687849

    Google Scholar 

  10. Gironell A, Kulisevsky J, Barbanoj M, Lopez-Villegas D, Hernandez G, Pascuai-Sedano B (1999) A randomized placebo-controlled comparative trial of gabapentin and propranolol in essential tremor. Arch Neurol 56(4):475–480. https://doi.org/10.1001/archneur.56.4.475

    Article  CAS  PubMed  Google Scholar 

  11. Bruno E, Nicoletti A, Quattrocchi G, Allegra R, Filippini G, Colosimo C, Zappia M (2017) Topiramate for essential tremor. Cochrane Database Syst Rev 4:CD009683. https://doi.org/10.1002/14651858.CD009683.pub2

    PubMed  Google Scholar 

  12. Stollberger C, Finsterer J (2016) Interactions between non-vitamin K oral anticoagulants and antiepileptic drugs. Epilepsy Res 126:98–101. https://doi.org/10.1016/j.eplepsyres.2016.06.003

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Northern Arizona VA Health Care System, 500 N Hwy 89, Prescott, AZ, 86313, USA

    Joseph P. Rindone & Chadwick K. Mellen

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  1. Joseph P. Rindone
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  2. Chadwick K. Mellen
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Correspondence to Joseph P. Rindone.

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Rindone, J.P., Mellen, C.K. Warfarin resistance from primidone in patient with essential tremor. Eur J Clin Pharmacol 74, 377–378 (2018). https://doi.org/10.1007/s00228-017-2382-4

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