Skip to main content
Log in

Acute neurological symptoms secondary to hypomagnesemia induced by proton pump inhibitors: a case series

  • Letter to the Editors
  • Published:
European Journal of Clinical Pharmacology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Furlanetto TW, Faulhaber GA (2011) Hypomagnesemia and proton pump inhibitors: below the tip of the iceberg. Arch Intern Med 171(15):1391–1392

    Article  PubMed  Google Scholar 

  2. Cundy T, Mackay J (2011) Proton pump inhibitors and severe hypomagnesaemia. Curr Opin Gastroenterol 27(2):180–185

    Article  CAS  PubMed  Google Scholar 

  3. Zipursky J, Macdonald EM, Hollands S, Gomes T, Mamdani MM, Paterson JM, Lathia N, Juurlink DN 2014 Proton pump inhibitors and hospitalization with hypomagnesemia: a population-based case-control study. PLoS Med 11(9)

  4. Pasina L, Zanotta D, Puricelli S, Djignefa DC, Bonoldi G (2015) Proton pump inhibitors and risk of hypomagnesemia. Eur J Intern Med 26(7):e25–e26

    Article  CAS  PubMed  Google Scholar 

  5. Park CH, Kim EH, Roh YH, Kim HY, Lee SK (2014) The association between the use of proton pump inhibitors and the risk of hypomagnesemia: a systematic review and meta-analysis. PLoS One 9(11). doi:10.1371/journal.pone.0112558

  6. Rosa RG, Barros AJ, de Lima AR, et al. (2014) Mood disorder as a manifestation of primary hypoparathyroidism: a case report. J Med Case Rep 8:326

    Article  PubMed  PubMed Central  Google Scholar 

  7. Deroux A, Khouri C, Chabre O, Bouillet L, Casez O (2014) Severe acute neurological symptoms related to proton pump inhibitors induced hypomagnesemia responsible for profound hypoparathyroidism with hypocalcemia. Clin Res Hepatol Gastroenterol 38(5):e103–e105

    Article  CAS  PubMed  Google Scholar 

  8. Hoorn EJ, van der Hoek J, de Man RA, Kuipers EJ, Bolwerk C, Zietse R (2010) A case series of proton pump inhibitor-induced hypomagnesemia. Am J Kidney Dis 56(1):112–116

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We are grateful to J.D. Baggott for editorial assistance.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Luca Pasina.

Ethics declarations

Conflict of interest

The authors declare that they have no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pasina, L., Zanotta, D., Puricelli, S. et al. Acute neurological symptoms secondary to hypomagnesemia induced by proton pump inhibitors: a case series. Eur J Clin Pharmacol 72, 641–643 (2016). https://doi.org/10.1007/s00228-016-2024-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00228-016-2024-2

Keywords

Navigation