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Hypoglycemia in venlafaxine overdose: a hypothesis of increased glucose uptake

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References

  1. Derijks HJ, Meyboom RH, Heerdink ER, De Koning FH, Janknegt R, Lindquist M, Egberts AC (2008) The association between antidepressant use and disturbances in glucose homeostasis: evidence from spontaneous reports. Eur J Clin Pharmacol 64:531–538. doi:10.1007/s00228-007-0441-y

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Khoza S, Barner JC (2011) Glucose dysregulation associated with antidepressant agents: an analysis of 17 published case reports. Int J Clin Pharm 33:484–492. doi:10.1007/s11096-011-9507-0

    Article  CAS  PubMed  Google Scholar 

  3. Francino MC, Bretaudeau Deguigne M, Badin J, Turcant A, Perrotin D (2012) Hypoglycaemia: a little known effect of venlafaxine overdose. Clin Toxicol 50:215–217. doi:10.3109/15563650.2012.660696

    Article  CAS  Google Scholar 

  4. Meertens JH, Monteban-Kooistra WE, Ligtenberg JJ, Tulleken JE, Zijlstra JG (2007) Severe hypoglycemia following venlafaxine intoxication: a case report. J Clin Psychopharmacol 27:414–415

    Article  PubMed  Google Scholar 

  5. Olefsky JM, Nolan JJ (1995) Insulin resistance and non-insulin-dependent diabetes mellitus: cellular and molecular mechanisms. Am J Clin Nutr 61:980S–986S

    CAS  PubMed  Google Scholar 

  6. Chi TC, Ho YJ, Chen WP, Chi TL, Lee SS, Cheng JT, Su MJ (2007) Serotonin enhances beta-endorphin secretion to lower plasma glucose in streptozotocin-induced diabetic rats. Life Sci 80:1832–1838

    Article  CAS  PubMed  Google Scholar 

  7. Sikka P, Kaushik S, Kumar G, Kapoor S, Bindra VK, Saxena KK (2011) Study of antinociceptive activity of SSRI (fluoxetine and escitalopram) and atypical antidepressants (venlafaxine and mirtazepine) and their interaction with morphine and naloxone in mice. J Pharm Bioallied Sci 3:412–416. doi:10.4103/0975-7406.84454

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  8. Bourne C, Gouraud A, Daveluy A, Grandvuillemin A, Auriche P, Descotes J, Vial T, French Association of Regional Pharmacovigilance Centres (2013) Tramadol and hypoglycaemia: comparison with other step 2 analgesic drugs. Br J Clin Pharmacol 75:1063–1067. doi:10.1111/j.1365-2125.2012.04451.x

    Article  CAS  PubMed Central  PubMed  Google Scholar 

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Correspondence to Miran Brvar.

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Brvar, M., Koželj, G. & Mašič, L.P. Hypoglycemia in venlafaxine overdose: a hypothesis of increased glucose uptake. Eur J Clin Pharmacol 71, 261–262 (2015). https://doi.org/10.1007/s00228-014-1784-9

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  • DOI: https://doi.org/10.1007/s00228-014-1784-9

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