Abstract
Aim
Our goal was to investigate the use of hypnosedatives (HSs) before and during hospitalization, explore the relationship between their use and various demographic and clinical variables, and compare the results with data from a similar 2000 study with particular interest in adherence to hospital formulary guidelines.
Methods
A cross-sectional observational survey of 326 hospitalized patients recruited from ten wards of the Ghent University Hospital, Gent, Belgium, with a patient interview and by evaluating medical and nursing files.
Results
In 30.7% of patients, the use of a HS before admission was reported. According to the patient interview, 33.1% used a HS during hospitalization. However, according to medical and nursing files, use of HSs in the hospital was 10% higher (43.3%). In 19.4% of patients who took HSs before admission, their use was discontinued in the hospital. In 15.6% of patients who took no HS before admission, a HS was started in the hospital, according to the formulary guidelines (data from files). There was a positive correlation between HS use in the hospital and older age, longer hospitalization, not coming from home, higher number of HSs taken before hospitalization, sleeping problems emerging during hospitalization, and central nervous system (CNS) disorders. In comparison with 2000, we registered a slight decrease in HS use during hospitalization and a decrease in the number of newly started patients.
Conclusions
The prevalence of HS use in our university hospital is high, mostly as a result of continuation of HSs started before admission, as there seems to be no general policy of active cessation. Compared with the survey performed 10 years ago, fewer hospitalized patients are newly started on HSs, and when this is the case, the formulary guidelines are followed.
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Acknowledgements
The authors are indebted to pharmacist F. Lavreau for her valuable help with data collection, to the participating heads of the medical departments, the head nurses, and to the participating patients. This study was not funded, and the authors have no conflicts of interest.
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Somers, A., Robays, H., Audenaert, K. et al. The use of hypnosedative drugs in a university hospital: has anything changed in 10 years?. Eur J Clin Pharmacol 67, 723–729 (2011). https://doi.org/10.1007/s00228-010-0983-2
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DOI: https://doi.org/10.1007/s00228-010-0983-2