Lower Jump Power Rather Than Muscle Mass Itself is Associated with Vertebral Fracture in Community-Dwelling Elderly Korean Women

Abstract

Sarcopenia is considered to be a risk factor for osteoporotic fracture, which is a major health problem in elderly women. In this study, we aimed to investigate the association of sarcopenia, with regard to muscle mass and function, with prevalent vertebral fracture in community-dwelling elderly women. We recruited 1281 women aged 64 to 87 years from the Korean Urban Rural Elderly cohort study. Muscle mass and function were measured using bioimpedance analysis and jumping mechanography. Skeletal muscle index (SMI) and jump power were used as an indicator of muscle mass and function, respectively. Among the participants, we observed 282 (18.9%) vertebral fractures and 564 (44.0%) osteoporosis. Although age, body mass index, and prevalence of osteoporosis increased as both SMI and jump power decreased, prevalence of vertebral fracture increased only when jump power decreased. In univariate analysis, compared with the highest quartile of jump power, the lowest quartile had a significant odds ratio of 2.80 (95% CI 1.79–4.36) for vertebral fracture. This association between jump power and vertebral fracture remained significant, with an odds ratio of 3.04 (95% CI 1.77–5.23), even after adjusting for other risk factors including age, bone mineral density, previous fracture, and cognitive function. In contrast, there was no association between SMI and vertebral fracture. Based on our results, low jump power, but not SMI, is associated with vertebral fracture in community-dwelling elderly Korean women. This finding suggests that jump power may have a more important role than muscle mass itself for osteoporotic fracture.

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Acknowledgements

The present study was supported by funding from the Korea Centers for Disease Control and Prevention (code 2011-E63005-00, 2012-E63001-001, 2013-E63007-00-02, and 2014-ER6306-00).

Authors’ Contributions

EYL designed the study, analyzed the data, and wrote the manuscript. SJL analyzed the data and wrote the manuscript. KMK, DS, SWL, and HSC collected the data and revised the manuscript. HCK, COK, and YY interpreted the data and revised the manuscript. YR designed the study, interpreted the data, and revised the manuscript.

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Correspondence to Yumie Rhee.

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Conflicts of interest

Eun Young Lee, Su Jin Lee, Kyoung Min Kim, Da Hae Seo, Seung Won Lee, Han Sol Choi, Hyeon Chang Kim, Yoosik Youm, Chang Oh Kim, and Yumie Rhee declare that they have no conflict of interest.

Ethical approval

The study protocol was approved by the ethics committee of Severance Hospital.

Informed consent

Participants provided written informed consent before enrolling in the study and completing the examination. Participants were informed that they could chose to withdraw from the study at any time. According to the International Conference on Harmonization Good Clinical Practice guidelines, all information recorded was anonymized.

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Eun Young Lee and Su Jin Lee have contributed equally to this manuscript.

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Lee, E.Y., Lee, S.J., Kim, K.M. et al. Lower Jump Power Rather Than Muscle Mass Itself is Associated with Vertebral Fracture in Community-Dwelling Elderly Korean Women. Calcif Tissue Int 100, 585–594 (2017). https://doi.org/10.1007/s00223-017-0239-6

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Keywords

  • Osteoporosis
  • Fracture
  • Sarcopenia
  • Jump power
  • Elderly