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Comment on Osteocytes: Masters Orchestrators of Bone

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References

  1. Aguirre JI, Plotkin LI, Stewart SA, Weinstein RS, Parfitt AM, Manolagas SC, Bellido T (2006) Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss. J Bone Min Res 21:605–615

    Article  Google Scholar 

  2. Bivi N, Condon KW, Allen MR, Farlow N, Passeri G, Brun L, Rhee Y et al (2012) Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation. J Bone Min Res 27:374–389

    Article  CAS  Google Scholar 

  3. Plotkin LI, Weinstein RS, Parfitt AM, Roberson PK, Manolagas SC, Bellido T (1999) Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. J Clin Invest 104:1363–1374

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  4. Plotkin LI, Manolagas SC, Bellido T (2002) Transduction of cell survival signals by connexin-43 hemichannels. J Biol Chem 277:8648–8657

    Article  PubMed  CAS  Google Scholar 

  5. Bivi N, Nelson MT, Faillace ME, Li J, Miller LM, Plotkin LI (2012) Deletion of Cx43 from osteocytes results in defective bone material properties but does not decrease extrinsic strength in cortical bone. Calcif Tissue Int 91:215–224

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  6. Bivi N, Pacheco-Costa R, Brun LR, Murphy TR, Farlow NR, Robling AG, Bellido T et al (2013) Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice. J Orthop Res 31:1075–1081

    Article  PubMed  CAS  Google Scholar 

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Conflict of interest

The authors have stated that they have no conflict of interest.

Human and Animal Rights and Informed Consent

The protocols involving mice were approved by the Institutional Animal Care and Use Committee of University of Arkansas for Medical Sciences and Indiana University School of Medicine.

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Authors and Affiliations

  1. Anatomy and Cell Biology, Indianapolis, IN, USA

    Lilian I. Plotkin & Teresita Bellido

  2. Medicine, Indiana University School of Medicine, Indianapolis, IN, USA

    Teresita Bellido

  3. Roudebush Veterans Administration Medical Center, Indianapolis, IN, USA

    Lilian I. Plotkin & Teresita Bellido

Authors
  1. Lilian I. Plotkin
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  2. Teresita Bellido
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Correspondence to Lilian I. Plotkin.

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Plotkin, L.I., Bellido, T. Comment on Osteocytes: Masters Orchestrators of Bone. Calcif Tissue Int 95, 382–383 (2014). https://doi.org/10.1007/s00223-014-9905-0

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  • DOI: https://doi.org/10.1007/s00223-014-9905-0

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