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Late-Onset Subcutaneous Scalp Calcifications in a Patient with Pseudo-Pseudohypoparathyroidism

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Abstract

Ectopic calcifications and even bone formation have been linked to GNAS gene mutations. A 51-year-old Caucasian female had been diagnosed of pseudo-pseudohypoparathyroidism (PPHP) in 1989. She has always had normal serum parathyroid hormone, calcium, and phosphorus levels. A non-contrast computed tomography of the head was done in 2013 and it showed finely speckled subcutaneous calcifications in the high convexity of the head. Cutaneous exploration did not show any abnormality. We herein report an unusual case of late-onset scalp calcifications in a patient with PPHP.

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Acknowledgments

We thank Dr L. Castaño from Cruces Hospital, Bilbao, for the genetic study. We also thank Dr M.T. García-Unzueta, Mrs B. Paule, and Mrs C. Rentería for biochemical determinations.

Human and Animal Rights and Informed Consent

The article was done with the approval of the local research ethics committee, in accordance with the Declaration of Helsinki, and with the written informed consent of the patient.

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Authors and Affiliations

  1. Department of Endocrinology, University Hospital “Marques de Valdecilla”, University of Cantabria, 39008, Santander, Cantabria, Spain

    Laura Ramos, María Piedra & José A. Amado

  2. Department of Radiology, University Hospital “Marques de Valdecilla”, University of Cantabria, 39008, Santander, Cantabria, Spain

    Elena Sánchez

  3. Fundación Instituto de Investigación Marqués de Valdecilla (IDIVAL), 39008, Santander, Cantabria, Spain

    Laura Ramos, María Piedra, Elena Sánchez & José A. Amado

Authors
  1. Laura Ramos
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  2. María Piedra
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  3. Elena Sánchez
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  4. José A. Amado
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Corresponding author

Correspondence to Laura Ramos.

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The authors declare that they have no conflicts of interest.

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Ramos, L., Piedra, M., Sánchez, E. et al. Late-Onset Subcutaneous Scalp Calcifications in a Patient with Pseudo-Pseudohypoparathyroidism. Calcif Tissue Int 95, 292–294 (2014). https://doi.org/10.1007/s00223-014-9890-3

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  • DOI: https://doi.org/10.1007/s00223-014-9890-3

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