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Treatment of Osteoporosis with Parathyroid Hormone and Teriparatide

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An Erratum to this article was published on 11 September 2009

Abstract

Nowadays osteoporosis treatment is based primarily on therapy with antiresorptive agents, like the bisphosphonates. Parathyroid hormone (Preotact) and human recombinant parathyroid hormone peptide 1–34 (Teriparatide) are relatively new for the treatment of osteoporosis and belong to the group of anabolic agents. Both agents demonstrated an increase in bone mineral density and a significant reduction in vertebral fractures in postmenopausal women with osteoporosis when given for 18–24 months. Data on nonvertebral fractures are, however, not clear-cut, and so far only bisphosphonates and strontium ranelate have been demonstrated to reduce all types of fractures and therefore remain the front-line option for treatment of osteoporosis. As the safety, tolerability, and cost of the therapy also influence the choice of therapy, Preotact and Teriparatide might be useful additions to the armamentarium for (second-line) treatment of osteoporosis.

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Authors and Affiliations

  1. 4th Medicine Department, Hanusch Hospital, Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, A-1140, Vienna, Austria

    Johannes Pleiner-Duxneuner, Elisabeth Zwettler, Eleftherios Paschalis, Paul Roschger, Valerie Nell-Duxneuner & Klaus Klaushofer

  2. Department of Clinical Pharmacology, Medical University Vienna, Vienna, Austria

    Johannes Pleiner-Duxneuner

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  1. Johannes Pleiner-Duxneuner
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  2. Elisabeth Zwettler
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  3. Eleftherios Paschalis
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  6. Klaus Klaushofer
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Correspondence to Johannes Pleiner-Duxneuner.

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An erratum to this article can be found at http://dx.doi.org/10.1007/s00223-009-9291-1

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Pleiner-Duxneuner, J., Zwettler, E., Paschalis, E. et al. Treatment of Osteoporosis with Parathyroid Hormone and Teriparatide. Calcif Tissue Int 84, 159–170 (2009). https://doi.org/10.1007/s00223-009-9218-x

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  • DOI: https://doi.org/10.1007/s00223-009-9218-x

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