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Acute Effects of an Oral Calcium Load on Markers of Bone Metabolism During Endurance Cycling Exercise in Male Athletes

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Abstract

Although sport and physical activity are generally considered as positive factors for bone metabolism some endurance trainings such as running and bicycling have few or no beneficial or even deleterious effects on bone mineral density. The present study was designed to investigate the acute effect of an intensive endurance cycling exercise on biochemical bone markers. Futrthermore, the effect of the oral intake of 1g calcium load, by drinking high-calcium mineral water, just prior to and during the exercise was checked. Twelve well-trained elite male triathletes aged 23-37 years were explored. The serum concentrations of calcium, phosphate, PTH, bone alkaline phosphatase (BALP) and C-terminal cross-linking telopeptide of type 1 collagen (CTX) were measured before, during and after a 60 min 80% VO2max cycle ergometer exercise. Since cycling exercise was accompanied by a reduction in plasma volume the total amount of biochemical bone markers was calculated. When the exercise was performed without calcium load both serum concentrations and total amount of CTX began to increase progressively 30 min after the start of the exericse and were still significantly elevated, by 45-50%, 2h after the end of the exercise. Ingestion of high-calcium mineral water completely suppressed the CTX reponse. By contrast serum concentrations and total amount of BALP fluctuated and showed no significant difference with or without calcium load. The present study demonstrates that the burst of osteoclastic activity acutely induced by an endurance cycling exercise can be suppressed by the previous intake of a calcium load afforded by drinking high-calcium mineral water.

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Acknowledgements

The authors thank the students, Mr. David Ravassat and Mr. Fahti Chelly for their assistance with the setting up of the cycling exercises and with the collection of blood samples. They thank also the athletes who volunteered for this study.

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Authors and Affiliations

  1. Faculté de Médecine Pitié-Salpêtrière, Service de Biochimie, Paris, France

    J. Guillemant & S. Guillemant

  2. Ecole Pratique des Hautes Etudes, Laboratoire de Nutrition Hydrominérale, Faculté de Médecine Pitié-Salpêtrière, Paris, France

    C. Accarie & S. Guillemant

  3. Service de Physiologie et Médecine du Sport, Hôpital de La Pitié, Paris, France

    G. Peres

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  1. J. Guillemant
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Correspondence to J. Guillemant.

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Guillemant, J., Accarie, C., Peres, G. et al. Acute Effects of an Oral Calcium Load on Markers of Bone Metabolism During Endurance Cycling Exercise in Male Athletes. Calcif Tissue Int 74, 407–414 (2004). https://doi.org/10.1007/s00223-003-0070-0

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