Analysis of mirror neuron system activation during action observation alone and action observation with motor imagery tasks
- 427 Downloads
This study aimed to explore the relationship between action observation (AO)-related corticomotor excitability changes and phases of observed action and to explore the effects of pure AO and concurrent AO and motor imagery (MI) state on corticomotor excitability using TMS. It was also investigated whether the mirror neuron system activity is muscle-specific. Fourteen healthy volunteers were enrolled in the study. EMG recordings were taken from the right first dorsal interosseous and the abductor digiti minimi muscles. There was a significant main effect of TMS timing (after the beginning of the movement, at the beginning of motor output state, and during black screen) on the mean motor evoked potential (MEP) amplitude. Mean MEP amplitudes for AO combined with MI were significantly higher than pure AO session. There was a significant interaction between session and TMS timing. There was no significant main effect of muscle on MEP amplitude. The results indicate that corticomotor excitability is modulated by different phases of the observed motor movement and this modulation is not muscle-specific. Simultaneous MI and AO enhance corticomotor excitability significantly compared to pure AO.
KeywordsAction observation Motor imagery Corticomotor excitability Transcranial magnetic stimulation
This work was supported by the Scientific and Technical Research Council of Turkey (TUBITAK) under Grant 114E621.
- Loporto M, Holmes PS, Wright DJ, McAllister CJ (2013) Reflecting on mirror mechanisms: motor resonance effects during action observation only present with low-intensity transcranial magnetic stimulation. PLoS One 8 (5), e64911Google Scholar
- Perry A, Stiso J, Edward F. Chang EF, Lin JJ, Parvizi J, Knight RT (2017). Mirroring in the human brain: deciphering the spatial-temporal patterns of the human mirror neuron system. Cereb Cortex. 30. https://doi.org/10.1093/cercor/bhx013
- Rozzi S, Ferrari PF, Bonini L, Rizzolatti G, Fogassi L (2008) Functional organization of inferior parietal lobule convexity in the macaque monkey: electrophysiological characterization of motor, sensory and mirror responses and their correlation with cytoarchitectonic areas. Eur J Neurosci 28:1569 – 1588CrossRefPubMedGoogle Scholar