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Evidence for reduced efficacy of the Ia-pathway during shortening plantar flexions with increasing effort

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Abstract

To determine whether the soleus (SOL) H-reflex is modulated during shortening contractions in a manner that has been observed for isometric contractions, SOL H-reflexes and M-waves were elicited via percutaneous electrical stimulation to the tibial nerve at an intensity that evoked an H-reflex at 50% of its maximum in 11 healthy subjects. Paired electrical stimuli were delivered as the ankle angle passed through 90° at an interval of 400 ms while the subject performed shortening contractions at levels of plantar flexion torque ranging between 2 and 30% of that during a maximal voluntary contraction (MVC). H-reflexes were also recorded during the performance of isomeric contractions of plantar flexors at similar levels of plantar flexion torque and at the same joint angle (muscle length) in an additional five healthy subjects. Correlations were examined between the peak-to-peak amplitude of the first H-reflexes, M-waves and plantar flexion torques in both protocols. It was revealed that no significant correlation was found between the SOL H-reflex and increasing plantar flexion torque during shortening contractions (ρ = −0.07, P = 0.15), while a strong positive correlation was observed for the isometric conditions (ρ = 0.99, P < 0.01). No significant change was observed in the SOL M-wave for either contraction type. Furthermore, the H-reflexes elicited via paired stimuli with the same background activity in voluntary shortening contractions showed almost identical amplitudes, suggesting that the level of homosynaptic post-activation depression did not change in response to the varying levels of activation in voluntary shortening contractions. Therefore, the lack of increase in the H-reflex during shortening contractions at increasing intensities is possibly due to a centrally regulated increase in presynaptic inhibition. Such a downward modulation of the reflex suggests that Ia-excitatory input onto the SOL motoneurone pool needs to be reduced during the performance of shortening contractions.

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References

  • Brooke JD, Cheng J, Collins DF, McIlroy WE, Misiaszek JE, Staines WR (1997) Sensori-sensory afferent conditioning with leg movement: gain control in spinal reflex and ascending paths. Prog Neurobiol 51:393–421

    Article  PubMed  CAS  Google Scholar 

  • Burke D, Gandevia SC, McKeon B (1984) Monosynaptic and oligosynaptic contributions to human ankle jerk and H-reflex. J Neurophysiol 52:435–448

    PubMed  CAS  Google Scholar 

  • Burke D, Adams RW, Skuse NF (1989) The effects of voluntary contraction on the H reflex of human limb muscles. Brain 112(Pt 2):417–433

    Article  PubMed  Google Scholar 

  • Butler AJ, Yue G, Darling WG (1993) Variations in soleus H-reflexes as a function of plantarflexion torque in man. Brain Res 632:95–104

    Article  PubMed  CAS  Google Scholar 

  • Capaday C, Stein RB (1986) Amplitude modulation of the soleus H-reflex in the human during walking and standing. J Neurosci 6:1308–1313

    PubMed  CAS  Google Scholar 

  • Capaday C, Stein RB (1987) Difference in the amplitude of the human soleus H reflex during walking and running. J Physiol 392:513–522

    PubMed  CAS  Google Scholar 

  • Crone C, Nielsen J (1989) Methodological implications of the post activation depression of the soleus H-reflex in man. Exp Brain Res 78:28–32

    Article  PubMed  CAS  Google Scholar 

  • Crone C, Hultborn H, Jespersen B, Nielsen J (1987) Reciprocal Ia inhibition between ankle flexors and extensors in man. J Physiol 389:163–185

    PubMed  CAS  Google Scholar 

  • Crone C, Hultborn H, Mazieres L, Morin C, Nielsen J, Pierrot-Deseilligny E (1990) Sensitivity of monosynaptic test reflexes to facilitation and inhibition as a function of the test reflex size: a study in man and the cat. Exp Brain Res 81:35–45

    Article  PubMed  CAS  Google Scholar 

  • Floeter MK, Kohn AF (1997) H-reflexes of different sizes exhibit differential sensitivity to low frequency depression. Electroencephalogr Clin Neurophysiol 105:470–475

    Article  PubMed  CAS  Google Scholar 

  • Guissard N, Duchateau J, Hainaut K (2001) Mechanisms of decreased motoneurone excitation during passive muscle stretching. Exp Brain Res 137:163–169

    Article  PubMed  CAS  Google Scholar 

  • Hultborn H, Illert M, Nielsen J, Paul A, Ballegaard M, Wiese H (1996) On the mechanism of the post-activation depression of the H-reflex in human subjects. Exp Brain Res 108:450–462

    Article  PubMed  CAS  Google Scholar 

  • Iles JF (1996) Evidence for cutaneous and corticospinal modulation of presynaptic inhibition of Ia afferents from the human lower limb. J Physiol 491(Pt 1):197–207

    PubMed  CAS  Google Scholar 

  • Jankowska E (1992) Interneuronal relay in spinal pathways from proprioceptors. Prog Neurobiol 38:335–378

    Article  PubMed  CAS  Google Scholar 

  • Kennedy PM, Cresswell AG (2001) The effect of muscle length on motor-unit recruitment during isometric plantar flexion in humans. Exp Brain Res 137:58–64

    Article  PubMed  CAS  Google Scholar 

  • Koceja DM, Trimble MH, Earles DR (1993) Inhibition of the soleus H-reflex in standing man. Brain Res 629:155–158

    Article  PubMed  CAS  Google Scholar 

  • Koerber HR, Mendell LM (1991) Modulation of synaptic transmission at Ia-afferent fiber connections on motoneurons during high-frequency stimulation: role of postsynaptic target. J Neurophysiol 65:590–597

    PubMed  CAS  Google Scholar 

  • Kohn AF, Floeter MK, Hallett M (1997) Presynaptic inhibition compared with homosynaptic depression as an explanation for soleus H-reflex depression in humans. Exp Brain Res 116:375–380

    Article  PubMed  CAS  Google Scholar 

  • Matthews PB (1986) Observations on the automatic compensation of reflex gain on varying the pre-existing level of motor discharge in man. J Physiol 374:73–90

    PubMed  CAS  Google Scholar 

  • Meunier S, Pierrot-Deseilligny E (1989) Gating of the afferent volley of the monosynaptic stretch reflex during movement in man. J Physiol 419:753–763

    PubMed  CAS  Google Scholar 

  • Meunier S, Pierrot-Deseilligny E (1998) Cortical control of presynaptic inhibition of Ia afferents in humans. Exp Brain Res 119:415–426

    Article  Google Scholar 

  • Nordlund MM, Thorstensson A, Cresswell AG (2002) Variations in the soleus H-reflex as a function of activation during controlled lengthening and shortening actions. Brain Res 952:301–307

    Article  PubMed  CAS  Google Scholar 

  • Nordlund MM, Thorstensson A, Cresswell AG (2004) Conditioning Ia-afferent stimulation reduces the soleus Hoffman reflex in humans when muscle spindles are assumed to be inactive. Neurosci Lett 366:250–253

    Article  PubMed  CAS  Google Scholar 

  • Pierrot-Deseilligny E (1997) Assessing changes in presynaptic inhibition of Ia afferents during movement in humans. J Neurosci Methods 74:189–199

    Article  PubMed  CAS  Google Scholar 

  • Pierrot-Deseilligny E, Burke D (2005) The circuitry of human spinal cord: its role in motor control and movement disorders. Cambrige University Press, Cambridge

    Google Scholar 

  • Pinniger GJ, Steele JR, Thorstensson A, Cresswell AG (2000) Tension regulation during lengthening and shortening actions of the human soleus muscle. Eur J Appl Physiol 81:375–383

    Article  PubMed  CAS  Google Scholar 

  • Pinniger GJ, Nordlund M, Steele JR, Cresswell AG (2001) H-reflex modulation during passive lengthening and shortening of the human triceps surae. J Physiol 534:913–923

    Article  PubMed  CAS  Google Scholar 

  • Riedo R, Ruegg DG (1988) Origin of the specific H reflex facilitation preceding a voluntary movement in man. J Physiol 397:371–388

    PubMed  CAS  Google Scholar 

  • Romano C, Schieppati M (1987) Reflex excitability of human soleus motoneurones during voluntary shortening or lengthening contractions. J Physiol 390:271–284

    PubMed  CAS  Google Scholar 

  • Rudomin P, Schmidt RF (1999) Presynaptic inhibition in the vertebrate spinal cord revisited. Exp Brain Res 129:1–37

    Article  PubMed  CAS  Google Scholar 

  • Schneider C, Capaday C (2003) Progressive adaptation of soleus H-reflex with daily training at walking backward. J Neurophysiol 89:648–656

    Article  PubMed  Google Scholar 

  • Smith AM (1981) The coactivation of antagonist muscles. Can J Physiol Pharmacol 59:733–747

    PubMed  CAS  Google Scholar 

  • Stein RB, Thompson AK (2006) Muscle reflexes in motion: how, what, and why? Exerc Sport Sci Rev 34:145–153

    Article  PubMed  Google Scholar 

  • Stein RB, Estabrooks KL, McGie S, Roth MJ, Jones KE (2007) Quantifying the effects of voluntary contraction and inter-stimulus interval on the human soleus H-reflex. Exp Brain Res 182:309–319

    Article  PubMed  Google Scholar 

  • Toft E, Sinkjaer T (1993) H-reflex changes during contractions of the ankle extensors in spastic patients. Acta Neurol Scand 88:327–333

    Article  PubMed  CAS  Google Scholar 

  • Touge T, Taylor JL, Rothwell JC (1998) Reduced excitability of the cortico-spinal system during the warning period of a reaction time task. Electroencephalogr Clin Neurophysiol 109:489–495

    Article  PubMed  CAS  Google Scholar 

  • Trimble MH, Du P, Brunt D, Thompson FJ (2000) Modulation of triceps surae H-reflexes as a function of the reflex activation history during standing and stepping. Brain Res 858:274–283

    Article  PubMed  CAS  Google Scholar 

  • Ugawa Y, Terao Y, Hanajima R, Sakai K, Kanazawa I (1995) Facilitatory effect of tonic voluntary contraction on responses to motor cortex stimulation. Electroencephalogr Clin Neurophysiol 97:451–454

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

The main experiment was supported by funding from the Swedish Research Council.

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Authors and Affiliations

  1. School of Human Movement Studies, The University of Queensland, Brisbane, QLD, 4072, Australia

    T. Oya & A. G. Cresswell

  2. Division of Physiotherapy, The University of Queensland, Brisbane, QLD, Australia

    A. G. Cresswell

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  1. T. Oya
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  2. A. G. Cresswell
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Correspondence to A. G. Cresswell.

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Oya, T., Cresswell, A.G. Evidence for reduced efficacy of the Ia-pathway during shortening plantar flexions with increasing effort. Exp Brain Res 185, 699–707 (2008). https://doi.org/10.1007/s00221-007-1198-3

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  • DOI: https://doi.org/10.1007/s00221-007-1198-3

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