European Food Research and Technology

, Volume 239, Issue 6, pp 1003–1014 | Cite as

The anti-inflammatory and wound healing properties of honey

  • Manjunatha Devagondanahalli HadagaliEmail author
  • Lee Suan Chua
Original Paper


Honey is a natural product produced by bees and has been used for thousands of years as a medicinal agent and dietary supplement. It is known to cure a wide variety of ailments and can be used as a potent anti-inflammatory and wound healing agent. These vital bioactivities of honey are far less well known than its antibacterial, antioxidant, and any other biological activities. Many clinical trials have been reported and revealed that, when honey is applied to wound, there is a decrease in inflammation and will have a soothing effect. There is much evidence for the anti-inflammatory and wound healing effects of honey in terms of publications in modern medical and scientific journals. The exact mechanism of anti-inflammatory activity and wound healing property of honey has yet to be demonstrated. Possibly there are several mechanisms of action. There are also some reports where honey exerts negligible side effects. The article focuses on the components of honey involved in its anti-inflammatory effect, possible mechanism of action, properties of honey responsible for its wound healing activity, and its adverse effects. Overall the review presents the evidence and explanation for the anti-inflammatory and wound healing properties of honey.


Honey Anti-inflammatory activity Mechanism of action Wound healing Side effects 


Conflict of interest


Compliance with Ethics Requirements

This article does not contain any studies with human or animal subjects.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Manjunatha Devagondanahalli Hadagali
    • 1
    Email author
  • Lee Suan Chua
    • 1
  1. 1.Metabolite Profiling Laboratory, Institute of Bioproduct DevelopmentUniversiti Teknologi MalaysiaJohor BahruMalaysia

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