Abstract
Phenolic antioxidants seem to be partly responsible for the protective effects against cardiovascular diseases attributed to moderate wine consumption. Grape skins greatly contribute to the phenolic composition of red wine. In this paper, the in vitro antioxidant activity of red grape (Vitis vinifera) skins is determined. We show that the radical scavenging activity (C 50 values) against 2,2-diphenyl-1-picrylhydrazyl (DPPH·) of grape skin extracts is relatively high (3.2–11.1 mg dried skin/mg DPPH·) in relation to other foodstuffs and, as expected, is influenced by grape variety, stage of grape ripening and vintage. The antioxidant potential of grape skins seems to be transferred into wine since grape varieties with skins exhibiting high antioxidant potential also resulted in wines with high antioxidant activity. Statistically significant correlations were found between antioxidant activity and phenolic content (total polyphenols, proanthocyanins, catechins and anthocyanins) for both grape skins and wines.
Similar content being viewed by others
References
Rimm EB, Klatsky A, Grobbee D, Stampfer MJ (1996) Br Med J 312:731–735
Soleas GJ, Diamandis EP, Goldberg DM (1997) J Clin Lab Anal 11:287–313
Stanley LL, Mazier MJP (1999) Nutr Res 19:3–15
Van de Wiel A, van Golde PHM, Hart HCh (2001) Eur J Int Med 12:484–489
Cheynier V, Moutounet M, Sarni-Manchado P (1998) In: Flanzy C (ed) Enologie: fondaments scientifiques et technologiques. Lavoisier, Cachan, pp 123–162
Frankel EN, Waterhouse AL, Teissedre PL (1995) J Agric Food Chem 43:890–894
Larrauri JA, Sánchez-Moreno C, Rupérez P, Saura-Calixto F (1999) J Agric Food Chem 47:1603–1606
Burns J, Gardner PT, O’Neil J, Crawford S, Morecroft I, McPhail DB, Lister C, Matthews D, MacLean MR, Lean MEJ, Duthie GG, Crozier A (2000) J Agric Food Chem 48:220–230
Landrault N, Poucheret P, Ravel P, Gase F, Cros G, Teissedre PL (2001) J Agric Food Chem 49:3341–3348
Dávalos A, Gómez-Cordovés C, Bartolomé B (2004) J Agric Food Chem (in press)
Manzocco L, Mastrocloa D, Nicoli MC (1999) Food Res Int 31:673–678
Hurtado I, Caldú P, Gonzalo A, Ramon JM, Mínguez S, Fiol C (1997) J Agric Food Chem 45:1283–1289
Burns J, Gardner PT, Matthews D, Duthie GG, Lean MEJ, Crozier A (2001) J Agric Food Chem 49:5797–5808
Wood JE, Senthilmohan ST, Peskin AV (2002) Food Chem 77:115–161
Jayaprakasha GK, Selvi T, Sakariah KK (2003) Food Res Int 36:117–122
Larrauri JA, Ruperez P, Saura-Calixto F (1996) Am J Enol Vitic 47:369–372
Bonilla F, Mayen M, Merida J, Medina M (1999) Food Chem 66:209–215
Murthy KNC, Singh RP, Jayaprakasha GK (2002) J Agric Food Chem 50:5909–5914
Shrikhande AJ (2000) Food Res Int 33:469–474
Brand-Williams W, Cuvelier ME, Berset C (1995) Lebensm Wiss Technol 28:25–30
Singleton VI, Rossi JA (1965) Am J Enol Vitic 16:144–158
Riberau-Gayon P, Stonestreet E (1966) Chem Anal 48:188–196
Swain T, Hillis WE (1959) J Sci Food Agric 10:63–69
Paronetto L (1977) Polifenoli e tecnica enologica. Selepress, Milan
Saint-Cricq de Galulejac N, Vivas N, Glories Y (1998) Rev Franc Oenol 173:22–25
De Ancos B, Gonzalez E, Cano MP (2000) J Agric Food Chem 48:3542–3548
Yan X, Murphy BT, Hammond GB, Vinson JA, Neto CC (2002) J Agric Food Chem 50:5844–5849
Dávalos A, Gómez-Cordovés C, Bartolomé B (2003) J Agric Food Chem 51:2512–2519
Dávalos A, Bartolomé B, Gómez-Cordovés C (2003) J Sci Food Agric (in press)
Gómez-Cordovés C, Bartolomé B, Vieira W, Virador VM (2003) J Agric Food Chem 49:1620–1624
De Beer D, Joubert E, Gelderblom WCA, Manley M (2003) J Agric Food Chem 51:902–909
Acknowledgements
The authors are grateful to Mr. Julián Suberviola (EVENA, Navarra, Spain) for providing the grape wine samples and to the Spanish Comisión Interministerial de Ciencia y Tecnología (CICYT) (Projects AGL2000-1427-C02-02 and AGL2003-01088) for funding.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bartolomé, B., Nuñez, V., Monagas, M. et al. In vitro antioxidant activity of red grape skins. Eur Food Res Technol 218, 173–177 (2004). https://doi.org/10.1007/s00217-003-0833-x
Received:
Revised:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00217-003-0833-x