Skip to main content
Log in

In vitro antioxidant activity of red grape skins

  • Original Paper
  • Published:
European Food Research and Technology Aims and scope Submit manuscript

Abstract

Phenolic antioxidants seem to be partly responsible for the protective effects against cardiovascular diseases attributed to moderate wine consumption. Grape skins greatly contribute to the phenolic composition of red wine. In this paper, the in vitro antioxidant activity of red grape (Vitis vinifera) skins is determined. We show that the radical scavenging activity (C 50 values) against 2,2-diphenyl-1-picrylhydrazyl (DPPH·) of grape skin extracts is relatively high (3.2–11.1 mg dried skin/mg DPPH·) in relation to other foodstuffs and, as expected, is influenced by grape variety, stage of grape ripening and vintage. The antioxidant potential of grape skins seems to be transferred into wine since grape varieties with skins exhibiting high antioxidant potential also resulted in wines with high antioxidant activity. Statistically significant correlations were found between antioxidant activity and phenolic content (total polyphenols, proanthocyanins, catechins and anthocyanins) for both grape skins and wines.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Rimm EB, Klatsky A, Grobbee D, Stampfer MJ (1996) Br Med J 312:731–735

    CAS  Google Scholar 

  2. Soleas GJ, Diamandis EP, Goldberg DM (1997) J Clin Lab Anal 11:287–313

    Article  CAS  PubMed  Google Scholar 

  3. Stanley LL, Mazier MJP (1999) Nutr Res 19:3–15

    Article  CAS  Google Scholar 

  4. Van de Wiel A, van Golde PHM, Hart HCh (2001) Eur J Int Med 12:484–489

    Article  Google Scholar 

  5. Cheynier V, Moutounet M, Sarni-Manchado P (1998) In: Flanzy C (ed) Enologie: fondaments scientifiques et technologiques. Lavoisier, Cachan, pp 123–162

  6. Frankel EN, Waterhouse AL, Teissedre PL (1995) J Agric Food Chem 43:890–894

    CAS  Google Scholar 

  7. Larrauri JA, Sánchez-Moreno C, Rupérez P, Saura-Calixto F (1999) J Agric Food Chem 47:1603–1606

    Article  CAS  PubMed  Google Scholar 

  8. Burns J, Gardner PT, O’Neil J, Crawford S, Morecroft I, McPhail DB, Lister C, Matthews D, MacLean MR, Lean MEJ, Duthie GG, Crozier A (2000) J Agric Food Chem 48:220–230

    Article  CAS  PubMed  Google Scholar 

  9. Landrault N, Poucheret P, Ravel P, Gase F, Cros G, Teissedre PL (2001) J Agric Food Chem 49:3341–3348

    Article  CAS  PubMed  Google Scholar 

  10. Dávalos A, Gómez-Cordovés C, Bartolomé B (2004) J Agric Food Chem (in press)

  11. Manzocco L, Mastrocloa D, Nicoli MC (1999) Food Res Int 31:673–678

    Article  Google Scholar 

  12. Hurtado I, Caldú P, Gonzalo A, Ramon JM, Mínguez S, Fiol C (1997) J Agric Food Chem 45:1283–1289

    Article  CAS  Google Scholar 

  13. Burns J, Gardner PT, Matthews D, Duthie GG, Lean MEJ, Crozier A (2001) J Agric Food Chem 49:5797–5808

    Article  CAS  PubMed  Google Scholar 

  14. Wood JE, Senthilmohan ST, Peskin AV (2002) Food Chem 77:115–161

    Article  Google Scholar 

  15. Jayaprakasha GK, Selvi T, Sakariah KK (2003) Food Res Int 36:117–122

    Article  CAS  Google Scholar 

  16. Larrauri JA, Ruperez P, Saura-Calixto F (1996) Am J Enol Vitic 47:369–372

    CAS  Google Scholar 

  17. Bonilla F, Mayen M, Merida J, Medina M (1999) Food Chem 66:209–215

    Article  CAS  Google Scholar 

  18. Murthy KNC, Singh RP, Jayaprakasha GK (2002) J Agric Food Chem 50:5909–5914

    Article  CAS  PubMed  Google Scholar 

  19. Shrikhande AJ (2000) Food Res Int 33:469–474

    Article  CAS  Google Scholar 

  20. Brand-Williams W, Cuvelier ME, Berset C (1995) Lebensm Wiss Technol 28:25–30

    CAS  Google Scholar 

  21. Singleton VI, Rossi JA (1965) Am J Enol Vitic 16:144–158

    CAS  Google Scholar 

  22. Riberau-Gayon P, Stonestreet E (1966) Chem Anal 48:188–196

    Google Scholar 

  23. Swain T, Hillis WE (1959) J Sci Food Agric 10:63–69

    CAS  Google Scholar 

  24. Paronetto L (1977) Polifenoli e tecnica enologica. Selepress, Milan

  25. Saint-Cricq de Galulejac N, Vivas N, Glories Y (1998) Rev Franc Oenol 173:22–25

    Google Scholar 

  26. De Ancos B, Gonzalez E, Cano MP (2000) J Agric Food Chem 48:3542–3548

    Article  PubMed  Google Scholar 

  27. Yan X, Murphy BT, Hammond GB, Vinson JA, Neto CC (2002) J Agric Food Chem 50:5844–5849

    Article  CAS  PubMed  Google Scholar 

  28. Dávalos A, Gómez-Cordovés C, Bartolomé B (2003) J Agric Food Chem 51:2512–2519

    Article  PubMed  Google Scholar 

  29. Dávalos A, Bartolomé B, Gómez-Cordovés C (2003) J Sci Food Agric (in press)

  30. Gómez-Cordovés C, Bartolomé B, Vieira W, Virador VM (2003) J Agric Food Chem 49:1620–1624

    Article  Google Scholar 

  31. De Beer D, Joubert E, Gelderblom WCA, Manley M (2003) J Agric Food Chem 51:902–909

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

The authors are grateful to Mr. Julián Suberviola (EVENA, Navarra, Spain) for providing the grape wine samples and to the Spanish Comisión Interministerial de Ciencia y Tecnología (CICYT) (Projects AGL2000-1427-C02-02 and AGL2003-01088) for funding.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Begoña Bartolomé.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bartolomé, B., Nuñez, V., Monagas, M. et al. In vitro antioxidant activity of red grape skins. Eur Food Res Technol 218, 173–177 (2004). https://doi.org/10.1007/s00217-003-0833-x

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00217-003-0833-x

Keywords

Navigation