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Determination of zinc in pharmaceutical products by use of a sequential injection analysis system

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Abstract.

A sequential injection analysis (SIA) system is proposed for the determination of zinc in pharmaceutical samples. The method is based on the spectrophotometric detection of zinc using xylenol orange as a colour reagent at 568 nm. The system can be used to monitor zinc at a frequency of 30 samples h–1 with an average recovery of ±98.5% and a relative standard deviation of less than 1%. A linear relationship between peak height and zinc concentration is obtained between 10 and 60 mg L–1. The results obtained are in good agreement with those obtained by use of a standard method.

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van Staden, K.J., Tsanwani, M. Determination of zinc in pharmaceutical products by use of a sequential injection analysis system. Fresenius J Anal Chem 371, 376–379 (2001). https://doi.org/10.1007/s002160100975

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  • DOI: https://doi.org/10.1007/s002160100975

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