Abstract
The Standard Reference Materials Program at the US National Institute of Standards and Technology (NIST) has three human DNA standard reference materials (SRM 2390, SRM 2391a, and SRM 2392) currently available1 (Orders and requests for information concerning these SRMs should be directed to the Standard Reference Materials Program, National Institute of Standards and Technology, 100 Bureau Drive, Stop 2321, Gaithersburg, MD 20899-2321, Telephone (301) 975-6776, FAX: (301) 948-3730.) [1, 2]. Both the DNA profiling SRM 2390 and the polymerase chain reaction (PCR)-based DNA profiling SRM 2391a are intended for use in forensic and paternity identifications, for instructional law enforcement, or for non-clinical research purposes and are not intended for clinical diagnostics. The mitochondrial DNA (mtDNA) SRM 2392 is to provide standardization and quality control when performing PCR and sequencing any segment or the entire 16,569 base pairs that comprise human mitochondrial DNA. SRM 2392 is designed for use by the forensic, medical, and toxicological communities for human identification, disease diagnosis or mutation detection.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 1 December 2000 / Revised: 19 February 2001 / Accepted: 22 February 2001
Rights and permissions
About this article
Cite this article
Levin, B., Cheng, H., Kline, M. et al. A review of the DNA standard reference materials developed by the National Institute of Standards and Technology. Fresenius J Anal Chem 370, 213–219 (2001). https://doi.org/10.1007/s002160100792
Issue Date:
DOI: https://doi.org/10.1007/s002160100792