Abstract
Simultaneous determination of six internationally authorised organic UV-filters in sunscreen formulations was performed by HPLC with UV spectrophotometric detection. The filters determined were: sulisobenzone, oxybenzone, octyl dimethyl PABA, octyl methoxycinnamate, octyl salicylate and homosalate. A C18 stationary phase and a mobile phase of ethanol water acetic acid (70 : 29.5 : 0.5) were used with a flow rate of 0.5 mL/min. UV measurements were carried out at 313 nm. The time required for the analysis was 25 min and the limits of detection were between 0.2 and 2 mg/L, except for sulisobenzone, which gave a limit of detection of 20 mg/L. The procedure proposed provides an accurate, fast and green analytical method, that does not involve toxic organic solvents.
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Received: 26 September 2000 / Revised: 14 December 2000 / Accepted: 19 December 2000
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Chisvert, A., Pascual-Martí, MC. & Salvador, A. Determination of UV-filters in sunscreens by HPLC. Fresenius J Anal Chem 369, 638–641 (2001). https://doi.org/10.1007/s002160100701
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DOI: https://doi.org/10.1007/s002160100701