Abstract
6-Mercaptopurine(6-MP) is covalently modified onto a silver electrode to construct a chemically modified electrode (CME). It exhibits the capability of selectively complexing myoglobin and can be applied as a selective biosensor for this compound. Myoglobin is accumulated onto the CME at 0.32 V (vs. SCE); after exchanging the medium it is determined by differential pulse stripping voltammetry. A cathodic stripping peak is obtained at 0.15 V (vs. SCE) by scanning the potential from 0.35 to –0.1 V. The peak currents are linearly proportional to the concentration of myoglobin in the range of 0.2 ∼ 4 μg/mL with a relative standard deviation of 7.8%. The detection limit is about 0.1 μg/mL. The mechanism of the complexation is also discussed.
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Received: 30 January 1997 / Revised: 7 May 1996 / Accepted: 10 May 1996
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Long, YT., Zhu, JJ. & Chen, HY. Preconcentration and voltammetric determination of trace myoglobin at a 6-mercaptopurine modified silver electrode. Fresenius J Anal Chem 360, 614–617 (1998). https://doi.org/10.1007/s002160050768
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DOI: https://doi.org/10.1007/s002160050768