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Determination of procaine hydrochloride by ion-pairing flow injection analysis with piezoelectric detection

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Abstract

A fast and simple method for the determination of procaine hydrochloride by ion-pairing flow injection analysis has been developed. It is based on the formation of an ion-pair with sodium dodecyl phenylsulphonate and piezoelectric detection. The calibration curve was linear between 0.02 and 2.00 mg/mL, with a detection limit of 0.01 mg/mL, a relative standard deviation of 0.3% (10 replicates) and a sampling frequency of 120/h. The proposed method has been satisfactorily applied to the determination of procaine hydrochloride in pharmaceutical preparations.

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Authors and Affiliations

  1. Department of Applied Chemistry, Sichuan Union University, Chengdu 610065, PR China, , , , , , CN

    Z. Mo, J. Luo & Xiaohui Long

  2. College of Chemistry and Chemical Engineering, Chongqing University, Chongqing 630044, PR China, , , , , , CN

    Ziling Xia

Authors
  1. Z. Mo
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  2. J. Luo
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  3. Xiaohui Long
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  4. Ziling Xia
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Received: 19 August 1996 / Revised: 6 November 1996 / Accepted: 12 December 1996

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Mo, Z., Luo, J., Long, X. et al. Determination of procaine hydrochloride by ion-pairing flow injection analysis with piezoelectric detection. Fresenius J Anal Chem 358, 556–558 (1997). https://doi.org/10.1007/s002160050469

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  • DOI: https://doi.org/10.1007/s002160050469

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