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Analytical and Bioanalytical Chemistry

, Volume 410, Issue 16, pp 3769–3778 | Cite as

Multielement analysis of Zanthoxylum bungeanum Maxim. essential oil using ICP-MS/MS

  • Liang Fu
  • Hualin Xie
  • Shuyun Shi
Research Paper

Abstract

The concentrations of trace elements (Cr, Ni, As, Cd, Hg, and Pb) in Zanthoxylum bungeanum Maxim. essential oil (ZBMEO) were determined by inductively coupled plasma tandem mass spectrometry. The ZBMEO sample was directly analyzed after simple dilution with n-hexane. Aiming for a relatively high vapor pressure of n-hexane and its resultant loading on plasma, we used a narrow injector torch and optimized plasma radio frequency power and carrier gas flow to ensure stable operation of the plasma. An optional gas flow of 20% O2 in Ar was added to the carrier gas to prevent the incomplete combustion of highly concentrated organic carbon in plasma and the deposition of carbon on the sampling and skimmer cone orifices. In tandem mass spectrometry mode, O2 was added to the collision/reaction cell to eliminate the interferences. The limits of detection for Cr, Ni, As, Cd, Hg, and Pb were 2.26, 1.64, 2.02, 1.35, 1.76, and 0.97 ng L-1, respectively. After determination of 23 ZBMEO samples from different regions in China, we found that the average concentration ranges of trace elements in the 23 ZBMEO samples were 0.72–6.02 ng g-1, 0.09–2.87 ng g-1, 0.21–5.84 ng g-1, 0.16–2.15 ng g-1, 0.13–0.92 ng g-1, and 0.17–0.73 ng g-1 for Cr, Ni, As, Cd, Hg, and Pb, respectively. The trace elements in ZBMEO differed significantly when different extraction technologies were used. The study revealed that the contents of the toxic elements As, Cd, Hg, and Pb were extremely low, and hence they are unlikely to pose a health risk following ZBMEO ingestion.

Graphical abstract

The working mechanism of sample analysis by ICP-MS/MS

Keywords

Zanthoxylum bungeanum Maxim. Essential oil Inductively coupled plasma tandem mass spectrometry n-Hexane Trace elements 

Notes

Acknowledgements

This work was supported by the National Natural Science Foundation of China (81603400) and the Scientific and Technological Research Program of Chongqing Municipal Education Commission (KJ1601224).

Compliance with ethical standards

This article does not contain any studies with humans or animals.

Conflict of interest

The authors declare that they have no competing interests.

References

  1. 1.
    Yang X. Aroma constituents and alkylamides of red and green Huajiao (Zanthoxylum bungeanum and Zanthoxylum schinifolium). J Agric Food Chem. 2008;56(5):1689–96.CrossRefPubMedGoogle Scholar
  2. 2.
    Zhang L, Wu HT, Yang FX, Zhang JH. Evaluation of Soxhlet extractor for one-step biodiesel production from Zanthoxylum bungeanum seeds. Fuel Process Technol. 2015;131:452–7.CrossRefGoogle Scholar
  3. 3.
    Wei S, Zhang H, Wang Y, Wang L, Li X, Wang Y, et al. Ultrasonic nebulization extraction-heating gas flow transfer-headspace single drop microextraction of essential oil from pericarp of Zanthoxylum bungeanum Maxim. J Chromatogr A. 2011;1218(29):4599–605.CrossRefPubMedGoogle Scholar
  4. 4.
    Gong Y, Huang Y, Zhou L, Shi X, Guo Z, Wang M, et al. Chemical composition and antifungal activity of the fruit oil of Zanthoxylum bungeanum Maxim. (Rutaceae) from China. J Essent Oil Res. 2009;21(2):174–8.CrossRefGoogle Scholar
  5. 5.
    Kumar V, Kumar S, Singh B, Kumar N. Quantitative and structural analysis of amides and lignans in Zanthoxylum armatum by UPLC-DAD-ESI-QTOF-MS/MS. J Pharmaceut Biomed. 2014;94(3):23–9.CrossRefGoogle Scholar
  6. 6.
    Chyau CC, Mao JL, Wu CM. Characteristics of the steam-distilled oil and carbon dioxide extract of Zanthoxylum simulans fruits. J Agric Food Chem. 1996;44(4):1096–9.CrossRefGoogle Scholar
  7. 7.
    Choe E, Min DB. Mechanisms and factors for edible oil oxidation. Compr Rev Food Sci F. 2006;5(4):169–86.CrossRefGoogle Scholar
  8. 8.
    Perello G, Marti-Cid R, Llobet JM, Domingo JL. Effects of various cooking processes on the concentrations of arsenic, cadmium, mercury, and lead in foods. J Agric Food Chem. 2008;56(23):11262–9.CrossRefPubMedGoogle Scholar
  9. 9.
    Chang LW, Magos L, Suzuki T. Toxicology of metals. Boca Raton: CRC Lewis Publishers; 1996.Google Scholar
  10. 10.
    Mendil D, Uluozlu OD, Tuzen M, Soylak M. Investigation of the levels of some element in edible oil samples produced in Turkey by atomic absorption spectrometry. J Hazard Mater. 2009;165(1-3):724–8.CrossRefPubMedGoogle Scholar
  11. 11.
    Canario CM, Katskov DA. Direct determination of Cd and Pb in edible oils by atomic absorption spectrometry with transverse heated filter atomizer. J Anal At Spectrom. 2005;20(12):1386–8.CrossRefGoogle Scholar
  12. 12.
    Vieira MA, de Oliveira LCC, Goncalves RA, de Souza V, de Campos RC (2009) Determination of As in vegetable oil and biodiesel by graphite furnace atomic absorption spectrometry. Energ Fuel 23(12):5942-5946.Google Scholar
  13. 13.
    Ansari R, Kazi TG, Jamali MK, Arain MB, Wagan MD, Jalbani N, et al. Variation in accumulation of heavy metals in different verities of sunflower seed oil with the aid of multivariate technique. Food Chem. 2009;115(1):318–23.CrossRefGoogle Scholar
  14. 14.
    Zhu F, Fan W, Wang X, Qu L, Yao S. Health risk assessment of eight heavy metals in nine varieties of edible vegetable oils consumed in China. Food Chem Toxicol. 2011;49(12):3081–5.CrossRefPubMedGoogle Scholar
  15. 15.
    Cindric IJ, Zeiner M, Steffan I. Trace elemental characterization of edible oils by ICP-AES and GFAAS. Microchem J. 2007;85(1):136–9.CrossRefGoogle Scholar
  16. 16.
    de Souza RM, Mathias BM, da Silveira CLP, Aucelio RQ (2005) Inductively coupled plasma optical emission spectrometry for trace multi-element determination in vegetable oils, margarine and butter after stabilization with propan-1-ol and water. Spectrochim Acta B 60(5):711-715.Google Scholar
  17. 17.
    Bakircioglu D, Kurtulus YB, Yurtsever S. Comparison of extraction induced by emulsion breaking, ultrasonic extraction and wet digestion procedures for determination of metals in edible oil samples in Turkey using ICP-OES. Food Chem. 2013;138(2-3):770–5.CrossRefPubMedGoogle Scholar
  18. 18.
    Llorent-Martinez EJ, Ortega-Barrales P, Fernandez-de Cordova ML, Dominguez-Vidal A, Ruiz-Medina A. Investigation by ICP-MS of trace element levels in vegetable edible oils produced in Spain. Food Chem. 2011;127(3):1257–62.CrossRefPubMedGoogle Scholar
  19. 19.
    Hsu WH, Jiang SJ, Sahayam AC. Determination of Cu, As, Hg and Pb in vegetable oils by electrothermal vaporization inductively coupled plasma mass spectrometry with palladium nanoparticles as modifier. Talanta. 2013;117(22):268–72.CrossRefPubMedGoogle Scholar
  20. 20.
    Chu YL, Jiang SJ. Speciation analysis of arsenic compounds in edible oil by ion chromatography-inductively coupled plasma mass spectrometry. J Chromatogr A. 2011;1218(31):5175–9.CrossRefPubMedGoogle Scholar
  21. 21.
    Benincasa C, Lewis J, Perri E, Sindona G, Tagarelli A. Determination of trace element in Italian virgin olive oils and their characterization according to geographical origin by statistical analysis. Anal Chim Acta. 2007;585(2):366–70.CrossRefPubMedGoogle Scholar
  22. 22.
    Savio M, Ortiz MS, Almeida CA, Olsina RA, Martinez LD, Gil RA. Multielemental analysis in vegetable edible oils by inductively coupled plasma mass spectrometry after solubilisation with tetramethylammonium hydroxide. Food Chem. 2014;159(6):433–8.CrossRefPubMedGoogle Scholar
  23. 23.
    Kannamkumarath SS, Wrobel K, Wrobel K, Caruso JA. Speciation of arsenic in different types of nuts by ion chromatography-inductively coupled plasma mass spectrometry. J Agric Food Chem. 2004;52(6):1458–63.CrossRefPubMedGoogle Scholar
  24. 24.
    Castillo JR, Jimenez MS, Ebdon L. Semiquantitative simultaneous determination of metals in olive oil using direct emulsion nebulization. J Anal At Spectrom. 1999;14(9):1515–8.CrossRefGoogle Scholar
  25. 25.
    Garrido MD, Frias I, Diaz C, Hardisson A. Concentrations of metals in vegetable edible oils. Food Chem. 1994;50(3):237–43.CrossRefGoogle Scholar
  26. 26.
    Nunes LS, Barbosa JTP, Fernandes AP, Lemos VA, dos Santos WNL, Korn MGA, Teixeira LSG (2011) Multi-element determination of Cu, Fe, Ni and Zn content in vegetable oils samples by high-resolution continuum source atomic absorption spectrometry and microemulsion sample preparation. Food Chem 127(2):780-783.Google Scholar
  27. 27.
    He M, Huang L, Zhao B, Chen B, Hu B. Advanced functional materials in solid phase extraction for ICP-MS determination of trace elements and their species - a review. Anal Chim Acta. 2017;973:1–24.CrossRefPubMedGoogle Scholar
  28. 28.
    Barela PS, Silva NA, Pereira JSF, Marques JC, Rodrigues LF, Moraes DP. Microwave-assisted digestion using diluted nitric acid for further trace elements determination in biodiesel by SF-ICP-MS. Fuel. 2017;204:85–90.CrossRefGoogle Scholar
  29. 29.
    Markiewicz B, Sajnog A, Lorenc W, Hanc A, Komorowicz I, Suliburska J, et al. Multielemental analysis of 18 essential and toxic elements in amniotic fluid samples by ICP-MS: Full procedure validation and estimation of measurement uncertainty. Talanta. 2017;174:122–30.CrossRefPubMedGoogle Scholar
  30. 30.
    Gunduz S, Akman S. Investigation of trace element contents in edible oils sold in Turkey using microemulsion and emulsion procedures by graphite furnace atomic absorption spectrophotometry. LWT Food Sci Technol. 2015;64(2):1329–33.CrossRefGoogle Scholar
  31. 31.
    Dugo G, La Pera L, La Torre GL, Giuffrida D (2004) Determination of Cd(II), Cu(II), Pb(II), and Zn(II) content in commercial vegetable oils using derivative potentiometric stripping analysis. Food Chem 87(4):639-645.Google Scholar
  32. 32.
    Almeida JS, Anunciacao TA, Brandao GC, Dantas AF, Lemos VA, Teixeira LSG. Ultrasound-assisted single-drop microextraction for the determination of cadmium in vegetable oils using high-resolution continuum source electrothermal atomic absorption spectrometry. Spectrochim Acta B. 2015;107:159–63.CrossRefGoogle Scholar
  33. 33.
    Botto RI, Zhu JJ. Use of an ultrasonic nebulizer with membrane desolvation for analysis of volatile solvents by inductively coupled plasma atomic emission spectrometry. J Anal At Spectrom. 1995;9(9):905–12.CrossRefGoogle Scholar
  34. 34.
    Sanchez R, Todoli JL, Lienemann CP, Mermet JM (2013) Determination of trace elements in petroleum products by inductively coupled plasma techniques: a critical review. Spectrochim Acta B 88:104-126.Google Scholar
  35. 35.
    D’Ilio S, Violante N, Majorani C, Petrucci F. Dynamic reaction cell ICP-MS for determination of total As, Cr, Se and V in complex matrices: still a challenge? A review. Anal Chim Acta. 2011;698(1-2):6–13.CrossRefPubMedGoogle Scholar
  36. 36.
    Yip YC, Sham WC. Applications of collision/reaction-cell technology in isotope dilution mass spectrometry. Trends Anal Chem. 2007;26(7):727–43.CrossRefGoogle Scholar
  37. 37.
    Tanner SD, Baranov VI, Bandura DR. Reaction cells and collision cells for ICP-MS: a tutorial review. Spectrochim Acta B. 2002;57(9):1361–452.CrossRefGoogle Scholar
  38. 38.
    Fernandez SD, Sugishama N, Encinar JR, Sanz-Medel A. Triple quad ICPMS (ICPQQQ) as a new tool for absolute quantitative proteomics and phosphoproteomics. Anal Chem. 2012;84(14):5851–7.CrossRefGoogle Scholar
  39. 39.
    Virgilio A, Amais RS, Amaral CDB, Fialho LL, Schiavo D, Nobrega JA. Reactivity and analytical performance of oxygen as cell gas in inductively coupled plasma tandem mass spectrometry. Spectrochim Acta B. 2016;126:31–6.CrossRefGoogle Scholar
  40. 40.
    He Q, Xing Z, Wei C, Fang X, Zhang S, Zhang X. Rapid screening of copper intermediates in Cu(i)-catalyzed azide-alkyne cycloaddition using a modified ICP-MS/MS platform. Chem Commun. 2016;52(69):10501–4.CrossRefGoogle Scholar
  41. 41.
    Balcaen L, Bolea-Fernandez E, Resano M, Vanhaecke F. Inductively coupled plasma - Tandem mass spectrometry (ICP-MS/MS): A powerful and universal tool for the interference-free determination of (ultra)trace elements - a tutorial review. Anal Chim Acta. 2015;894:7–19.CrossRefPubMedGoogle Scholar
  42. 42.
    Magnusson B, Ornemark U. Eurachem guide: the Fitness for purpose of analytical methods - a laboratory guide to method validation and related topics, 2nd ed. 2014.Google Scholar
  43. 43.
    Chang YT, Jiang SJ. Determination of As, Cd and Hg in emulsified vegetable oil by flow injection chemical vapour generation inductively coupled plasma mass spectrometry. J Anal At Spectrom. 2008;23(1):140–4.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.College of Chemistry and Chemical EngineeringCentral South UniversityChangshaChina
  2. 2.College of Chemistry and Chemical EngineeringYangtze Normal UniversityChongqingChina

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