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Development of a kelp powder (Thallus laminariae) Standard Reference Material

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Abstract

A Standard Reference Material (SRM) of seaweed, SRM 3232 Kelp Powder (Thallus laminariae) has been developed to support food and dietary supplement measurements in compliance with the Food Safety Modernization Act (FSMA) and the Dietary Supplement Health and Education Act of 1994 (DSHEA). The material was characterized for nutritional minerals, arsenic species, isomers of vitamin K1, proximates, and toxic elements. Kelp is a rich source of vitamins and minerals, and it is an excellent source of dietary iodine. Kelp also contains a large amount of arsenic, which is toxic as inorganic species but much less so as organic species. To capture the dietary profile of kelp, certified values were issued for As, Ca, Cd, Cr, Cu, Fe, Hg, I, K, Mg, Mn, Mo, Na, Pb, and Zn. Reference values for proximates were assigned. For the first time, a certified value for iodine, reference values for isomers of vitamin K1, and reference values for arsenic species including arsenosugars were assigned in a seaweed. SRM 3232 fills a gap in Certified Reference Materials (CRMs) needed for quality assurance and method validation in the compositional measurements of kelp and similar seaweeds used as food and as dietary supplements.

Arsenic species and isomers of vitamin K1 were determined in the development of SRM 3232 Kelp Powder (Thallus laminariae).

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Acknowledgments

Support for the development of SRM 3232 was provided in part by the Office of Dietary Supplements of the National Institutes of Health (NIH-ODS). A gift of arsenosugar As(328) from Dr. John T. Creed of the U.S. Environmental Protection Agency, National Exposure Research Laboratory in Cincinnati, OH is gratefully acknowledged.

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Authors and Affiliations

  1. Chemical Sciences Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA

    Lee L. Yu, Joseph F. Browning, Carolyn Q. Burdette, George C. Caceres, Kaitlyn D. Chieh, W. Clay Davis, Brittany L. Kassim, Stephen E. Long, Karen E. Murphy, Rabia Oflaz, Rick L. Paul, Katherine E. Sharpless, Laura J. Wood & Rolf Zeisler

  2. Statistical Engineering Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA

    James H. Yen

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  1. Lee L. Yu
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Correspondence to Lee L. Yu.

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Yu, L.L., Browning, J.F., Burdette, C.Q. et al. Development of a kelp powder (Thallus laminariae) Standard Reference Material. Anal Bioanal Chem 410, 1265–1278 (2018). https://doi.org/10.1007/s00216-017-0766-z

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