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Glucose sensors based on electrospun nanofibers: a review

Analytical and Bioanalytical Chemistry volume 408, pages 1285–1306 (2016)Cite this article

Abstract

The worldwide increase in the number of people suffering from diabetes has been the driving force for the development of glucose sensors. The recent past has devised various approaches to formulate glucose sensors using various nanostructure materials. This review presents a combined survey of these various approaches, with emphasis on the current progress in the use of electrospun nanofibers and their composites. Outstanding characteristics of electrospun nanofibers, including high surface area, porosity, flexibility, cost effectiveness, and portable nature, make them a good choice for sensor applications. Particularly, their nature of possessing a high surface area makes them the right fit for large immobilization sites, resulting in increased interaction with analytes. Thus, these electrospun nanofiber-based glucose sensors present a number of advantages, including increased life time, which is greatly needed for practical applications. Taking all these facts into consideration, we have highlighted the latest significant developments in the field of glucose sensors across diverse approaches.

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Acknowledgments

S.A. and B.B. thank the Scientific and Technological Research Council of Turkey (TÜBITAK) (TÜBITAK-BIDEB 2216, Research Fellowship Programme for Foreign Citizens) for postdoctoral fellowship funding. T.U. acknowledges partial support of The Turkish Academy of Sciences – Outstanding Young Scientists Award Program (TUBA-GEBIP).

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  1. UNAM-National Nanotechnology Research Center, Bilkent University, Ankara, 06800, Turkey

    Anitha Senthamizhan, Brabu Balusamy & Tamer Uyar

  2. Institute of Materials Science and Nanotechnology, Bilkent University, Ankara, 06800, Turkey

    Tamer Uyar

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  1. Anitha Senthamizhan
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  2. Brabu Balusamy
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Correspondence to Anitha Senthamizhan, Brabu Balusamy or Tamer Uyar.

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Published in the topical collection Fiber-based Platforms for Bioanalytics with guest editors Antje J. Baeumner and R. Kenneth Marcus.

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Senthamizhan, A., Balusamy, B. & Uyar, T. Glucose sensors based on electrospun nanofibers: a review. Anal Bioanal Chem 408, 1285–1306 (2016). https://doi.org/10.1007/s00216-015-9152-x

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  • DOI: https://doi.org/10.1007/s00216-015-9152-x

Keywords

  • Biosensors
  • Nanofibers
  • Electrospinning
  • Glucose
  • Nanomaterials