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Raman spectroscopic characterisation of resin-infiltrated hypomineralised enamel

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Abstract

Raman spectroscopy was used to investigate how the effect of pre-treatment protocols, with combinations of hydrochloric acid (HCl), sodium hypochlorite (NaOCl) and hydrogen peroxide (H2O2), for molar–incisor hypo-mineralisation (MIH) altered the penetration depth of polymer infiltrants (ICON, DMG, Hamburg, Germany). Furthermore, the effect on the structure of the MIH portions of the teeth with treatment is examined using multivariate analysis of spectra. It was found that pre-treatment protocols improved penetration depths. The structure of the MIH portion post-treatment appeared much closer to that of normal enamel suggesting a diminution of protein in the MIH region with treatment.

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Acknowledgments

Arun Natarajan and Sara Fraser would like to acknowledge the University of Otago for postgraduate publishing bursaries.

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Authors and Affiliations

  1. Department of Oral Sciences, Faculty of Dentistry, University of Otago, PO Box 647, Dunedin, 9054, New Zealand

    Arun K. Natarajan & Bernadette K. Drummond

  2. Biomaterials Science Research Unit, Faculty of Dentistry, University of Sydney, Sydney Dental Hospital, Surry Hills, NSW, 2010, Australia

    Michael V. Swain

  3. MacDiarmid Institute of Advanced Materials and Nanotechnology, Department of Chemistry, University of Otago, PO Box 56, Dunedin, 9054, New Zealand

    Sara J. Fraser & Keith C. Gordon

  4. Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

    Sara J. Fraser

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  1. Arun K. Natarajan
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  2. Sara J. Fraser
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  3. Michael V. Swain
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  4. Bernadette K. Drummond
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  5. Keith C. Gordon
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Correspondence to Sara J. Fraser or Keith C. Gordon.

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Natarajan, A.K., Fraser, S.J., Swain, M.V. et al. Raman spectroscopic characterisation of resin-infiltrated hypomineralised enamel. Anal Bioanal Chem 407, 5661–5671 (2015). https://doi.org/10.1007/s00216-015-8742-y

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  • DOI: https://doi.org/10.1007/s00216-015-8742-y

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