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Single gold nanorods as optical probes for spectral imaging

Analytical and Bioanalytical Chemistry volume 407, pages 4029–4034 (2015)Cite this article

Abstract

In this paper, we explain in detail the wavelength dependence of the elastic scattering pattern of individual, optically isolated gold nanorods by using confocal microscopy in combination with higher order laser modes, i.e., radially/azimuthally polarized laser modes. We demonstrate that the spectral dependence of the scattering pattern is mostly caused by the relative strength of the gold nanorods’ plasmonic modes at different wavelengths. Since the gold nanorods’ plasmonic modes are determined by the particles’ geometrical parameter, e.g., size and aspect ratio, as well as the refractive index of the surrounding medium, we show that the spectral dependence of the scattering pattern is a simple, not invasive way to determine, e.g., the gold nanorod aspect ratio or physical variation of the local environment. Thus, a further development of spectral imaging of gold nanorods can lead to the employment of this technique in biomedical assays involving also living samples.

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Acknowledgments

This work was supported by the “BW Netz Funktionelle Nanostrukturen” and partly by DFG SPP 1391 ultrafast nanooptics.

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Affiliations

  1. Institute of Physical and Theoretical Chemistry, Eberhard Karls University Tuebingen, Auf der Morgenstelle 18, 72076, Tübingen, Germany

    Frank Wackenhut, Antonio Virgilio Failla & Alfred J. Meixner

  2. University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany

    Antonio Virgilio Failla

Authors
  1. Frank Wackenhut
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  2. Antonio Virgilio Failla
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  3. Alfred J. Meixner
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Corresponding authors

Correspondence to Antonio Virgilio Failla or Alfred J. Meixner.

Additional information

Published in the topical collection Direct Optical Detection with guest editors Guenter Gauglitz and Jiri Homola.

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Wackenhut, F., Failla, A.V. & Meixner, A.J. Single gold nanorods as optical probes for spectral imaging. Anal Bioanal Chem 407, 4029–4034 (2015). https://doi.org/10.1007/s00216-015-8642-1

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  • DOI: https://doi.org/10.1007/s00216-015-8642-1

Keywords

  • Gold nanorod
  • Particle plasmon
  • Elastic scattering
  • Confocal microscopy
  • Optical detection