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Pesticide residue analysis in cereal-based baby foods using multi-walled carbon nanotubes dispersive solid-phase extraction

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Abstract

In the present study, a new analytical method has been developed for the simultaneous quantification of 15 organophosphorus pesticides, including some of their metabolites, (disulfoton-sulfoxide, ethoprophos, cadusafos, dimethoate, terbufos, disulfoton, chlorpyrifos-methyl, malaoxon, fenitrothion, pirimiphos-methyl, malathion, chlorpyrifos, terbufos-sulfone, disulfoton-sulfone and fensulfothion) in three different types of commercial cereal-based baby foods. Dispersive solid-phase extraction (dSPE) with multi-walled carbon nanotubes (MWCNTs) was used together with gas chromatography with nitrogen phosphorus detection. Most favorable conditions involved a previous ultrasound-assisted extraction of the sample with acetonitrile containing formic acid. After evaporation of the extract and redissolution in water, a dSPE procedure was carried out with MWCNTs. The whole method was validated in terms of repeatability, linearity, precision and accuracy and matrix effect was also evaluated. Absolute recoveries were in the range 64–105 % with relative standard deviation values below 7.6 %. Limits of quantification achieved ranged from 0.31 to 5.50 μg/kg, which were lower than the European Union maximum residue limits for pesticide residues in cereal-based baby foods.

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References

  1. Ciecierska M, Obiedziński MW (2010) Food Control 21:1166–1172

    Article  CAS  Google Scholar 

  2. Rey-Salgueiro L, Martínez-Carballo E, García-Falcón MS, González-Barreiro C, Simal-Gándara J (2009) Food Chem 115:814–819

    Article  CAS  Google Scholar 

  3. Brera C, Debegnach F, De Santis B, Pannunzi E, Berdini C, Prantera E, Gregori E, Miraglia M (2011) Talanta 83:1442–1446

    Article  CAS  Google Scholar 

  4. D’Arco G, Fernández-Franzón M, Font G, Damiani P, Mañes J (2008) J Chromatogr A 1209:188–194

    Article  Google Scholar 

  5. Leandro CC, Hancock P, Fussell RJ, Keely BJ (2006) J Chromatogr A 1103:94–101

    Article  CAS  Google Scholar 

  6. Leandro CC, Hancock P, Fussell RJ, Keely BJ (2007) J Chromatogr A 1144:161–169

    Article  CAS  Google Scholar 

  7. Monitoring of pesticide residues in products of plant origin in the EU, Norway, Iceland and Liechtenstein. http://ec.europa.eu/food/fvo/specialreports/pesticides_index_en.htm, Accessed 1 Feb. 2012

  8. Leandro CC, Fussell RJ, Keely BJ (2005) J Chromatogr A 1085:207–212

    Article  CAS  Google Scholar 

  9. González-Curbelo MA, Hernández-Borges J, Borges-Miquel TM, Rodríguez-Delgado MA (2012) Food Addit Contam 29:104–116

    Article  Google Scholar 

  10. Duan AH, Xie SM, Yuan LM (2011) Trac-Trend Anal Chem 30:484–491

    Article  CAS  Google Scholar 

  11. Valcárcel M, Cárdenas S, Simonet BM, Moliner-Martínez Y, Lucena R (2008) Trac-Trend Anal Chem 27:34–43

    Article  Google Scholar 

  12. Li XS, Wu JH, Xu LD, Zhao Q, Luo YB, Yuan BF, Feng YQ (2011) Chem Commun 47:9816–9818

    Article  CAS  Google Scholar 

  13. Jacobs CB, Peairs MJ, Venton BJ (2010) Anal Chim Acta 662:105–127

    Article  CAS  Google Scholar 

  14. Ma J, Xiao R, Li J, Yu J, Zhang Y (2010) Chen L 1217:5462–5469

    CAS  Google Scholar 

  15. Ravelo-Pérez LM, Herrera-Herrera AV, Hernández-Borges J, Rodríguez-Delgado MA (2010) J Chromatogr A 1217:2618–2641

    Article  Google Scholar 

  16. Pyrzynska K (2011) Chemosphere 83:1407–1413

    Article  CAS  Google Scholar 

  17. Du D, Wang M, Zhang J, Cai J, Tu H, Zhang A (2008) Electrochem Commun 10:85–89

    Article  CAS  Google Scholar 

  18. Ravelo-Pérez LM, Hernández-Borges J, Rodríguez-Delgado MA (2008) J Chromatogr A 1211:33–42

    Article  Google Scholar 

  19. López-Feria S, Cárdenas S, Valcárcel M (2009) J Chromatogr A 1216:7346–7350

    Article  Google Scholar 

  20. Tsai WH, Huang TC, Huang JJ, Hsue YH, Chuang HY (2009) J Chromatogr A 1216:2263–2269

    Article  CAS  Google Scholar 

  21. Lu Q, Chen X, Nie L, Jiang H, Chen L, Hu Q, Du S, Zhang Z (2010) Talanta 81:959–966

    Article  CAS  Google Scholar 

  22. Peng Y, Xie Y, Luo J, Nie L, Chen Y, Chen L, Du S, Zhang Z (2010) Anal Chim Acta 674:190–200

    Article  CAS  Google Scholar 

  23. Asensio-Ramos M, D’Orazio G, Hernández-Borges J, Rocco A, Fanali S (2011) Anal Bioanal Chem 400:1113–1123

    Article  CAS  Google Scholar 

  24. Herrera-Herrera AV, Ravelo-Pérez LM, Hernández-Borges J, Afonso MM, Palenzuela J, Rodríguez-Delgado MA (2011) J Chromatogr A 1218:5352–5361

    Article  CAS  Google Scholar 

  25. Morales-Cid G, Fakete A, Simonet BM, Lehmann R, Cárdenas S, Zhang X, Valcárcel M, Schmitt-Kopplin P (2010) Anal Chem 82:2743–2752

    Article  CAS  Google Scholar 

  26. Ding J, Gao Q, Li XS, Huang W, Shi ZG, Feng YQ (2011) J Sep Sci 34:2498–2504

    Article  CAS  Google Scholar 

  27. Pardasani D, Kanaujia PK, Purohit AK, Shrivastava AR, Dubey DK (2011) Talanta 86:248–255

    Article  CAS  Google Scholar 

  28. Asensio-Ramos M, Hernández-Borges J, Borges-Miquel TM, Rodríguez-Delgado MA (2009) Anal Chim Acta 647:167–176

    Article  CAS  Google Scholar 

  29. Lee SJ, Park HJ, Kim W, Jin JS, El-Aty AMA, Shim JH, Shin SC (2009) Biomed Chromatogr 23:434–442

    Article  CAS  Google Scholar 

  30. Liu X, Xu J, Li Y, Dong F, Li J, Song W, Zheng Y (2011) Anal Bioanal Chem 399:2539–2547

    Article  CAS  Google Scholar 

  31. Chung SWC, Chen BLS (2011) J Chromatogr A 1218:5555–5567

    Article  CAS  Google Scholar 

  32. Gilbert-López B, García-Reyes JF, Molina-Díaz A (2009) Talanta 79:109–128

    Article  Google Scholar 

  33. Koesukwiwat U, Sanguankaew K, Leepipatpiboon N (2008) Anal Chim Acta 626:10–20

    Article  CAS  Google Scholar 

  34. Poole CF (2007) J Chromatogr A 1158:241–250

    Article  CAS  Google Scholar 

  35. Commission Directive 2003/13/EC of 10 February 2003 amending Directive 96/5/EC on processed cereal-based foods and baby foods for infants and young children, Off. J. Eur. Commun. L41 (2003)

  36. Căjka T, Hajšlová J, Lacina O, Maštovská K, Lehotay SJ (2008) J Chromatogr A 1186:281–294

    Article  Google Scholar 

  37. Georgakopoulos P, Mylona A, Athanasopoulos P, Drosinos EH, Skandamis PN (2009) Food Chem 115:1164–1169

    Article  CAS  Google Scholar 

  38. Căjka T, Maštovská K, Lehotay SJ, Hajšlová J (2005) J Sep Sci 28:1048–1060

    Article  Google Scholar 

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Acknowledgments

M.A.G.C., M.A.R. and A.V.H.H. wish to thank the Spanish Ministry of Education for the FPU grant at the University of La Laguna. J.H.B. thanks the Spanish Ministry of Science and Innovation for the Ramón y Cajal contract at the University of La Laguna. This work has been supported by the Spanish Ministry of Science and Innovation (project AGL2009-07884).

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Authors and Affiliations

  1. Departamento de Química Analítica, Nutrición y Bromatología, Facultad de Química, Universidad de La Laguna (ULL), Avenida Astrofísico Francisco Sánchez, s/no. 38206, La Laguna, Tenerife, Spain

    Miguel Ángel González-Curbelo, María Asensio-Ramos, Antonio V. Herrera-Herrera & Javier Hernández-Borges

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  1. Miguel Ángel González-Curbelo
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  2. María Asensio-Ramos
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  3. Antonio V. Herrera-Herrera
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  4. Javier Hernández-Borges
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Corresponding author

Correspondence to Javier Hernández-Borges.

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González-Curbelo, M.Á., Asensio-Ramos, M., Herrera-Herrera, A.V. et al. Pesticide residue analysis in cereal-based baby foods using multi-walled carbon nanotubes dispersive solid-phase extraction. Anal Bioanal Chem 404, 183–196 (2012). https://doi.org/10.1007/s00216-012-6103-7

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  • DOI: https://doi.org/10.1007/s00216-012-6103-7

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