Skip to main content

Colorimetric detection of oligonucleotides using a polydiacetylene vesicle sensor

Analytical and Bioanalytical Chemistry volume 382, pages 1708–1710 (2005)Cite this article

Abstract

A new system for the colorimetric detection of oligonucleotides was developed using polydiacetylene vesicles, which play the dual role of an indicator of color transition and an amplification tag. The results are of significance in understanding the mechanism of color transition of biological recognition in polydiacetylene systems and in designing new biosensors.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

References

  1. Nicewarner-Pena SR, Freeman RG, Reiss BD, He L, Pena DJ, Walton ID, Cromer R, Keating CD, Natan MJ (2001) Science 294:137–141

    Article  CAS  PubMed  Google Scholar 

  2. Zhao XJ, Tapec-Dytioco R, Tan WH (2003) J Am Chem Soc 125:11474–11475

    Article  CAS  PubMed  Google Scholar 

  3. Yu CJ, Wan YJ, Yowanto H, Li J, Tao CL, James MD, Tan CL, Blackburn GF, Meade TJ (2001) J Am Chem Soc 123:11155–11161

    Article  CAS  PubMed  Google Scholar 

  4. Park S-J, Taton TA, Mirkin CA (2002) Science 295:1503–1506

    Article  CAS  PubMed  Google Scholar 

  5. Ma ZF, Li JR, Jiang L, Yang M, Sui SF (2002) Chem Lett 3:328–329

    Article  Google Scholar 

  6. Leclerc M (1999) Adv Mater 11:1491–1498

    Article  CAS  Google Scholar 

  7. Ho HA, Boissinot M, Bergeron MG, Corbeil G, Dore K, Boudreau D, Leclerc M (2002) Angew Chem Int Ed 41:1548–1551

    Article  CAS  Google Scholar 

  8. Okada S, Peng S, Spevak W, Charych DH (1998) Acc Chem Res 31:229–239

    Article  CAS  Google Scholar 

  9. Jelinek R, Kolusheva S (2001) Biotechnol Adv 19:109–118

    Article  CAS  PubMed  Google Scholar 

  10. Nallicheri RA, Runer MF (1991) Macromolecules 24:517–525

    Article  CAS  Google Scholar 

  11. Carpick RW, Sasaki DY, Burns AR (2000) Langmuir 16:1270–1278

    Article  CAS  Google Scholar 

  12. Carpick RW, Mayer TM, Sasaki DY, Burns AR (2000) Langmuir 16:4639–4647

    Article  CAS  Google Scholar 

  13. Lee DC, Sahoo SK, Cholli AL, Sandman DJ (2002) Macromolecules 35:4347–4355

    Article  CAS  Google Scholar 

  14. Deckert AA, Fallon L, Kiernan L, Cashin C, Perrone A, Encalarde T (1994) Langmuir 10:1948–1954

    Article  CAS  Google Scholar 

  15. Ma ZF, Li JR, Liu MH, Cao J, Zou ZY, Tu J, Jiang L (1998) J Am Chem Soc 120:12678–12679

    Article  CAS  Google Scholar 

  16. Ma ZF, Li JR, Jiang L, Cao J, Boullanger P (2000) Langmuir 16:7801–7804

    Article  CAS  Google Scholar 

  17. Gill I, Ballesteros A (2003) Angew Chem Int Ed 42:3264–3267

    Article  CAS  Google Scholar 

  18. Reichert A, Nagy JO, Spevak W, Charych DH (1995) J Am Chem Soc 117:829–830

    Article  CAS  Google Scholar 

  19. Pan JJ, Charych DH (1997) Langmuir 13:1365–1367

    Article  CAS  Google Scholar 

  20. Kolusheva S, Shahal T, Jelinek R (2000) J Am Chem Soc 122:776–780

    Article  CAS  Google Scholar 

  21. Jonas U, Shah K, Norvez S, Charych DH (1999) J Am Chem Soc 121:4580–4588

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This research was supported by the National Natural Science Foundation of China (NSFC, No.20443011), Northeast Normal University, China, and Science and Technology Office of Jilin province.

Author information

Affiliations

  1. Chemistry Department, Northeast Normal University, Changchun 130024, P. R. China

    Chungang Wang & Zhanfang Ma

Authors
  1. Chungang Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zhanfang Ma
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Zhanfang Ma.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Wang, C., Ma, Z. Colorimetric detection of oligonucleotides using a polydiacetylene vesicle sensor. Anal Bioanal Chem 382, 1708–1710 (2005). https://doi.org/10.1007/s00216-005-3345-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00216-005-3345-7

Keywords

  • Polydiacetylene vesicles
  • Oligonucleotide detection