Abstract
The magnetic field-induced migration of particles in liquids is a highly-promising technique for the micro-separation analysis of bioparticles, such as cells and large DNA. Here, new methods that make use of magnetophoresis and electromagnetophoresis to induce the migration of microparticles in liquids are briefly reviewed. Magnetic force and Lorentz force are utilized in the new methods. Some typical examples of the use of these methods are described, and the advantages of using a superconducting magnet for them are demonstrated.
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Giddings JC, Brantley SL (1984) Separ Sci Technol 19:631–651
Vickrey TM, Garcia-Ramirez JA (1980) Separ Sci Technol 15:1297–1304
Schunk TC, Gorse J, Burke MF (1984) Separ Sci Technol 19:653–666
Levin S, Giddings JC (1991) J Chem Technol Biot 50:43–56
Fuh CB (2000) Anal Chem 72:266A-271A
Fuh CB, Chen SY (1998) J Chromatogr A 813:313–324
Fuh CB, Chen SY (1999) J Chromatogr A 857:193–204
Fuh CB, Lai JZ, Chang CM (2001) J Chromatogr A 923:263–270
Chalmers JJ, Zborowski M, Sun L, Moore L (1998) Biotechnol Progr 14:141–148
Zborowski M, Sun L, Moore LR, Williams PS, Chalmers JJ (1999) J Magn Magn Mater 194:224–230
Williams PS, Zborowski M, Chalmers JJ (1999) Anal Chem 71:3799–3807
Moore LR, Rodriguez AR, Williams PS, McCloskey K, Bolwell BJ, Nakamura M, Chalmers JJ, Zborowski M (2001) J Magn Magn Mater 225:227–284
Watarai H, Namba M (2001) Anal Sci 17:i169-i171
Watarai H, Namba M (2002) J Chromatogr A 961:3–8
Reddy S, Moore LR, Sun L, Zborowski M, Chalmers JJ (1996) Chem Eng Sci 51:947–956
Chalmers JJ, Zhao Y, Nakamura M, Melnik K, Lasky L, Moore L, Zborowski M (1999) J Magn Magn Mater 194:231–241
McCloskey KE, Comella K, Chalmers JJ, Margel S, Zborowski M (2001) Biotechnol Bioeng 75:642–655
McCloskey KE, Moore LR, Hoyos M, Rodriguez A, Chalmers JJ, Zborowski M (2003) Biotechnol Progr 19:899–907
Chosy EJ, Nakamura M, Melnik, Comella K, Lasky LC, Zborowski M, Chalmers JJ (2003) Biotechnol Bioeng 82:340–351
Wilhelm C, Gazeau F, Bacri JC (2002) Eur Biophys J 31:118–125
Suwa M, Watarai H (2001) Anal Chem 73:5214–5219
Suwa M, Watarai H (2002) Anal Chem 74:5027–5032
Suwa M, Watarai H (2003) J Chromatogr A (in press)
Kolin A (1953) Science 117:134–137
Happel J, Benner H (1965) Low Reynolds number hydrodynamics. Prentice-Hall, Englewood Cliffs, NJ
Karni Z, Kopito LE (1975) Med Biol Eng 13:457–462
Razee S, Tamura A, Masujima T (1994) Chem Pharm Bull 42:2376–2378
Kolin A (1967) J Chromatogr 26:164–179
Kolin A (1967) J Chromatogr 26:180–193
Kolin A, Kado RT (1958) Nature 182:510–512
Nalbandian RM, Michel RE, Mader I (1968) Experientia 24:1006–1007
Rice CL, Whitehead R (1964) J Chem Phys 41:2202
Namba M, Watarai H (2000) Anal Sci 16:5-9
Iiguni Y, Watarai H (2003) J Chromatogr A (submitted)
Iiguni Y, Watarai H (2003) Anal Sci 19:33–39
Israelachvili JN (1992) Intermolecular and surface forces, 2nd edn. Academic, New York
Klein JD, Clapp AR, Dickinson RB (2003) J Colloid Interf Sci 261:379–385
Iiguni Y, Watarai H (2003) Anal Chem (submitted)
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Watarai, H., Suwa, M. & Iiguni, Y. Magnetophoresis and electromagnetophoresis of microparticles in liquids. Anal Bioanal Chem 378, 1693–1699 (2004). https://doi.org/10.1007/s00216-003-2354-7
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DOI: https://doi.org/10.1007/s00216-003-2354-7