Skip to main content
Log in

Magnetophoresis and electromagnetophoresis of microparticles in liquids

  • Review
  • Published:
Analytical and Bioanalytical Chemistry Aims and scope Submit manuscript

Abstract

The magnetic field-induced migration of particles in liquids is a highly-promising technique for the micro-separation analysis of bioparticles, such as cells and large DNA. Here, new methods that make use of magnetophoresis and electromagnetophoresis to induce the migration of microparticles in liquids are briefly reviewed. Magnetic force and Lorentz force are utilized in the new methods. Some typical examples of the use of these methods are described, and the advantages of using a superconducting magnet for them are demonstrated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

References

  1. Giddings JC, Brantley SL (1984) Separ Sci Technol 19:631–651

    CAS  Google Scholar 

  2. Vickrey TM, Garcia-Ramirez JA (1980) Separ Sci Technol 15:1297–1304

    CAS  Google Scholar 

  3. Schunk TC, Gorse J, Burke MF (1984) Separ Sci Technol 19:653–666

    CAS  Google Scholar 

  4. Levin S, Giddings JC (1991) J Chem Technol Biot 50:43–56

    CAS  Google Scholar 

  5. Fuh CB (2000) Anal Chem 72:266A-271A

    Article  CAS  PubMed  Google Scholar 

  6. Fuh CB, Chen SY (1998) J Chromatogr A 813:313–324

    Article  Google Scholar 

  7. Fuh CB, Chen SY (1999) J Chromatogr A 857:193–204

    Article  CAS  PubMed  Google Scholar 

  8. Fuh CB, Lai JZ, Chang CM (2001) J Chromatogr A 923:263–270

    Article  CAS  PubMed  Google Scholar 

  9. Chalmers JJ, Zborowski M, Sun L, Moore L (1998) Biotechnol Progr 14:141–148

    Article  CAS  Google Scholar 

  10. Zborowski M, Sun L, Moore LR, Williams PS, Chalmers JJ (1999) J Magn Magn Mater 194:224–230

    Article  CAS  Google Scholar 

  11. Williams PS, Zborowski M, Chalmers JJ (1999) Anal Chem 71:3799–3807

    Article  CAS  PubMed  Google Scholar 

  12. Moore LR, Rodriguez AR, Williams PS, McCloskey K, Bolwell BJ, Nakamura M, Chalmers JJ, Zborowski M (2001) J Magn Magn Mater 225:227–284

    Google Scholar 

  13. Watarai H, Namba M (2001) Anal Sci 17:i169-i171

    Google Scholar 

  14. Watarai H, Namba M (2002) J Chromatogr A 961:3–8

    Article  CAS  PubMed  Google Scholar 

  15. Reddy S, Moore LR, Sun L, Zborowski M, Chalmers JJ (1996) Chem Eng Sci 51:947–956

    Article  CAS  Google Scholar 

  16. Chalmers JJ, Zhao Y, Nakamura M, Melnik K, Lasky L, Moore L, Zborowski M (1999) J Magn Magn Mater 194:231–241

    Article  CAS  Google Scholar 

  17. McCloskey KE, Comella K, Chalmers JJ, Margel S, Zborowski M (2001) Biotechnol Bioeng 75:642–655

    Article  CAS  PubMed  Google Scholar 

  18. McCloskey KE, Moore LR, Hoyos M, Rodriguez A, Chalmers JJ, Zborowski M (2003) Biotechnol Progr 19:899–907

    Article  CAS  Google Scholar 

  19. Chosy EJ, Nakamura M, Melnik, Comella K, Lasky LC, Zborowski M, Chalmers JJ (2003) Biotechnol Bioeng 82:340–351

    Article  CAS  PubMed  Google Scholar 

  20. Wilhelm C, Gazeau F, Bacri JC (2002) Eur Biophys J 31:118–125

    Article  CAS  PubMed  Google Scholar 

  21. Suwa M, Watarai H (2001) Anal Chem 73:5214–5219

    Article  CAS  PubMed  Google Scholar 

  22. Suwa M, Watarai H (2002) Anal Chem 74:5027–5032

    Article  CAS  PubMed  Google Scholar 

  23. Suwa M, Watarai H (2003) J Chromatogr A (in press)

  24. Kolin A (1953) Science 117:134–137

    Google Scholar 

  25. Happel J, Benner H (1965) Low Reynolds number hydrodynamics. Prentice-Hall, Englewood Cliffs, NJ

  26. Karni Z, Kopito LE (1975) Med Biol Eng 13:457–462

    CAS  PubMed  Google Scholar 

  27. Razee S, Tamura A, Masujima T (1994) Chem Pharm Bull 42:2376–2378

    CAS  Google Scholar 

  28. Kolin A (1967) J Chromatogr 26:164–179

    Article  CAS  Google Scholar 

  29. Kolin A (1967) J Chromatogr 26:180–193

    Article  CAS  Google Scholar 

  30. Kolin A, Kado RT (1958) Nature 182:510–512

    CAS  PubMed  Google Scholar 

  31. Nalbandian RM, Michel RE, Mader I (1968) Experientia 24:1006–1007

    CAS  PubMed  Google Scholar 

  32. Rice CL, Whitehead R (1964) J Chem Phys 41:2202

    CAS  Google Scholar 

  33. Namba M, Watarai H (2000) Anal Sci 16:5-9

    CAS  Google Scholar 

  34. Iiguni Y, Watarai H (2003) J Chromatogr A (submitted)

  35. Iiguni Y, Watarai H (2003) Anal Sci 19:33–39

    CAS  PubMed  Google Scholar 

  36. Israelachvili JN (1992) Intermolecular and surface forces, 2nd edn. Academic, New York

  37. Klein JD, Clapp AR, Dickinson RB (2003) J Colloid Interf Sci 261:379–385

    Article  CAS  Google Scholar 

  38. Iiguni Y, Watarai H (2003) Anal Chem (submitted)

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hitoshi Watarai.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Watarai, H., Suwa, M. & Iiguni, Y. Magnetophoresis and electromagnetophoresis of microparticles in liquids. Anal Bioanal Chem 378, 1693–1699 (2004). https://doi.org/10.1007/s00216-003-2354-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00216-003-2354-7

Keywords

Navigation