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Effects of alcohol hangover on simulated highway driving performance

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Abstract

Background

The purpose of this study was to examine the effects of alcohol hangover on simulated highway driving performance.

Methods

Driving performance of forty-two social drinkers was tested the morning following an evening of consuming on average 10.2 (SD = 4.2) alcoholic drinks (alcohol hangover) and on a control day (no alcohol consumed). Subjects performed a standardized 100-km highway driving test in the STISIM driving simulator. In addition to the standard deviation of lateral position (SDLP; i.e., the weaving of the car), lapses of attention were examined. Self-reported driving quality and driving style were scored, as well as mental effort to perform the test, sleepiness before and after driving, and hangover severity.

Results

Driving performance was significantly impaired during alcohol hangover as expressed by an SDLP increase of +1.9 cm (t (1,41) = 2.851, p = 0.007), increased number of lapses relative to the control day (7.7 versus 5.3 lapses, t (1,41) = 2.125, p = 0.019), and an increased total lapse time (182.7 versus 127.3 s, p = 0.040). During alcohol hangover, subjects reported their driving quality to be significantly poorer (t (1,41) = 4.840, p = 0.001) and less safe (t (1,41) = 5.078, p = 0.001), wise (t (1,41) = 4.061, p = 0.001), predictable (t (1,41) = 3.475, p = 0.001), and responsible (t (1,41) = 4.122, p = 0.001). Subjects further reported being significantly more tense while driving (t (1,41) = 3.280, p = 0.002), and more effort was needed to perform the driving test (t (1,41) = 2.941, p = 0.001). There was a significant interaction with total sleep time and hangover effects on SDLP and the number of lapses.

Conclusions

In conclusion, driving is significantly impaired during alcohol hangover, as expressed in an elevated SDLP and increased number of lapses. Total sleep time has a significant impact on the magnitude of driving impairment.

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References

  • Åkerstedt T, Gillberg M (1990) Subjective and objective sleepiness in the active individual. Int J Neurosci 52:29–37

    Article  PubMed  Google Scholar 

  • Brookhuis KA, De Waard D, Samyn N (2004) Effects of MDMA (ecstacy), and multiple drug use on (simulated) driving performance and traffic safety. Psychopharmacology 173:440–445

    Article  CAS  PubMed  Google Scholar 

  • Helland A, Jenssen GD, Lervåg LE, Westin AA, Moen T, Sakshaug K, Lydersen S, Mørland J, Slørdal L (2013) Comparison of driving simulator performance with real driving after alcohol intake: a randomised, single blind, placebo-controlled, cross-over trial. Accid Anal Prev 53:9–16

    Article  PubMed  Google Scholar 

  • Howland J, Rohsenow DJ, Edwards EM (2008) Are some drinkers resistant to hangover? A literature review. Curr Drug Abuse Rev 1:42–46

    Article  PubMed  Google Scholar 

  • Kennedy RS, Lane NE, Berbaum KS, Lilienthal MG (1993) Simulator sickness questionnaire: an enhanced method for quantifying simulator sickness. Int J Aviat Psychol 3:203–220

    Article  Google Scholar 

  • Kim DJ, Kim W, Yoon SJ, Choi BM, Kim JS, Go HJ, Kim YK, Jeong J (2003) Effects of alcohol hangover on cytokine production in healthy subjects. Alcohol 31:167–170

    Article  CAS  PubMed  Google Scholar 

  • Laska E, Meisner M, Wanderling J (2012) A maximally selected test of symmetry about zero. Stat Med 31:3178–3191

    Article  PubMed  Google Scholar 

  • Laurell H, Törnros J (1983) Investigation of alcoholic hangover effects on driving performance. Blut Alcohol 20:489–499

    Google Scholar 

  • Ling J, Stephens R, Heffernan TM (2010) Cognitive and psychomotor performance during alcohol hangover. Curr Drug Abuse Rev 3:80–87

    Article  PubMed  Google Scholar 

  • Louwerens JW, Gloerich ABM, De Vries G, Brookhuis KA, O’Hanlon JF (1987) The relationship between drivers’ blood alcohol concentration (BAC) and actual driving performance during high speed travel. In: Noordzij PC, Roszbach R (eds) Alcohol, drugs and traffic safety-T86. Excerpta Medica, Amsterdam, pp 183–183

    Google Scholar 

  • McCormick IA, Walkey FH, Green DE (1987) Comparative perceptions of driver ability—a confirmation and expansion. Accid Anal Prev 18:205–208

    Article  Google Scholar 

  • McKinney A, Coyle K (2004) Next day effects of a normal night's drinking on memory and psychomotor performance. Alcohol Alcohol 39:509–513

    Article  PubMed  Google Scholar 

  • McKinney A, Coyle K (2006) Alcohol hangover effects on measures of affect the morning after a normal night's drinking. Alcohol Alcohol 41:54–60

    Article  PubMed  Google Scholar 

  • Meijman TF, Thunnissen MJ, de Vries-Griever AGH (1990) The after-effects of a prolonged period of day-sleep on subjective sleep quality. Work Stress 4:65–70

    Article  Google Scholar 

  • Mets MA, Kuipers E, de Senerpont Domis LM, Leenders M, Olivier B, Verster JC (2011) Effects of alcohol on highway driving in the STISIM driving simulator. Hum Psychopharmacol 26:434–439

    CAS  PubMed  Google Scholar 

  • O’Hanlon JF, Haak TW, Blauw GJ, Riemersma JBJ (1982) Diazepam impairs lateral position control in highway driving. Science 217:79–81

    Google Scholar 

  • Penning R, McKinney A, Verster JC (2012) Alcohol hangover symptoms and their contribution to overall hangover severity. Alcohol Alcoholism 47:248–252

    Google Scholar 

  • Penning R, van Nuland M, Fliervoet LA, Olivier B, Verster JC (2010) The pathology of alcohol hangover. Curr Drug Abuse Rev 3:68–75

    Article  CAS  PubMed  Google Scholar 

  • Penning R, McKinney A, Bus LD, Olivier B, Slot K, Verster JC (2013) Measurement of alcohol hangover severity: development of the Alcohol Hangover Severity Scale (AHSS). Psychopharmacology 225:803–810

    Article  CAS  PubMed  Google Scholar 

  • Roehrs T, Beare D, Zorick F, Roth T (1994) Sleepiness and ethanol effects on simulated driving. Alcohol Clin Exp Res 8:154–158

    Article  Google Scholar 

  • Rohsenow DJ, Howland J, Minsky S, Greece J, Almeida A, Roehrs TA (2007) The acute hangover scale: a new measure of immediate hangover symptoms. Addict behav 32:1314–1320

    Article  PubMed Central  PubMed  Google Scholar 

  • Stephens R, Ling J, Heffernan TM, Heather N, Jones K (2008) A review of the literature on the cognitive effects of alcohol hangover. Alcohol Alcohol 43:163–170

    Article  PubMed  Google Scholar 

  • Törnros J, Laurell H (1991) Acute and hangover effects of alcohol on simulated driving performance. Blut Alcohol 28:24–30

    Google Scholar 

  • Verster JC, Roth T (2011) Standard operation procedures for conducting the on-the-road driving test, and measurement of the standard deviation of lateral position (SDLP). Int J Gen Med 4:359–371

    Article  PubMed Central  PubMed  Google Scholar 

  • Verster JC, Roth T (2012) Predicting psychopharmacological drug effects on actual driving (SDLP) from psychometric tests measuring driving-related skills. Psychopharmacology 220(2):293–301

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Verster JC, Stephens R, Penning R, Rohsenow D, McGeary J, Levy D, McKinney A, Finnigan F, Piasecki TM, Adan A, Batty GD, Fliervoet LAL, Heffernan T, Howland J, Kim D-J, Kruisselbrink LD, Ling J, McGregor N, Murphy RJL, van Nuland M, Oudelaar AM, Parkes A, Prat G, Reed N, Slutske WS, Smith G, Young M, on behalf of the Alcohol Hangover Research Group (2010) The Alcohol Hangover Research Group consensus statement on best practice in alcohol hangover research. Curr Drug Abuse Rev 3:116–127

    Article  PubMed Central  PubMed  Google Scholar 

  • Verster JC, Tiplady B, McKinney A (2012) Mobile technology and naturalistic study designs in addiction research. Curr Drug Abuse Rev 5:169–171

    Article  PubMed  Google Scholar 

  • Verster JC, van der Maarel M, McKinney A, Olivier B, de Haan L (2014a) Driving during alcohol hangover among Dutch professional truck drivers. Traffic Inj Prev. doi:10.1080/15389588.2013.833329

    Google Scholar 

  • Verster JC, Bervoets AC, de Klerk S, Roth T (2014b) Lapses of attention as outcome measure of the on-the-road driving test. Psychopharmacology 231:283–292

    Google Scholar 

Download references

Acknowledgments

Thanks to Gene Laska for his help with the symmetry analysis and Pieter van Dorp van Vliet for the artwork.

Conflict of interest

This study was funded by Utrecht University.

Joris Verster has received grants/research support from the Dutch Ministry of Infrastructure and the Environment, Takeda, and Red Bull and has acted as a consultant for the Canadian Beverage Association, Centraal Bureau Drogisterijbedrijven, Coleman Frost, Deenox, Purdue, Red Bull, Sanofi-Aventis, Sepracor, Takeda, Transcept, and Trimbos Institute.

Thomas Roth has received grants/research support from Aventis, Cephalon, GlaxoSmithKline, Neurocrine, Pfizer, Sanofi, Schering-Plough, Sepracor, Somaxon, Syrex, Takeda, TransOral, Wyeth, and Xenoport; has acted as a consultant for Abbott, Acadia, Acoglix, Actelion, Alchemers, Alza, Ancil, Arena, AstraZeneca, Aventis, AVER, BMS, BTG, Cephalon, Cypress, Dove, Elan, Eli Lilly, Evotec, Forest, GlaxoSmithKline, Hypnion, Impax, Intec, Intra-Cellular, Jazz, Johnson & Johnson, King, Lundbeck, McNeil, MediciNova, Merck, Neurim, Neurocrine, Neurogen, Novartis, Orexo, Organon, Prestwick, Procter & Gamble, Pfizer, Purdue, Resteva, Roche, Sanofi, Schering-Plough, Sepracor, Servier, Shire, Somaxon, Syrex, Takeda, TransOral, Vanda, Vivometrics, Wyeth, Yamanuchi, and Xenoport.

Berend Olivier is a scientific advisor for Emotional Brain BV and has received research support from Emotional Brain, PsychoGenics Inc, Sepracor, Servier, Abbott, and the Dutch Brain Research Organization.

Karel Brookhuis has received grants/research support from NWO, the Dutch Ministry of Infrastructure and the Environment, European Commission, Wyeth, Sanofi, Schering, Nissan, JARI, Mercedes Benz, and Verbond van Verzekeraars.

The other authors have no potential conflicts of interest to disclose.

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Authors and Affiliations

  1. Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands

    Joris C. Verster, Adriana C. Bervoets, Suzanne de Klerk, Rick A. Vreman & Berend Olivier

  2. Centre for Human Psychopharmacology, Swinburne University, Melbourne, VIC, 3122, Australia

    Joris C. Verster

  3. Sleep Disorders and Research Center, Henry Ford Health System, Detroit, MI, USA

    Thomas Roth

  4. Faculty of Behavioral and Social Sciences, Groningen University, Groningen, The Netherlands

    Karel A. Brookhuis

Authors
  1. Joris C. Verster
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  2. Adriana C. Bervoets
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  3. Suzanne de Klerk
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  4. Rick A. Vreman
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  5. Berend Olivier
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  6. Thomas Roth
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  7. Karel A. Brookhuis
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Correspondence to Joris C. Verster.

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Verster, J.C., Bervoets, A.C., de Klerk, S. et al. Effects of alcohol hangover on simulated highway driving performance. Psychopharmacology 231, 2999–3008 (2014). https://doi.org/10.1007/s00213-014-3474-9

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  • DOI: https://doi.org/10.1007/s00213-014-3474-9

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