References
Hajek P, McRobbie H, Myers K, Stapleton JA, Dhanji AR (2011) Varenicline treatment for four weeks prior to quitting smoking reduces ad-lib smoking and increases smoking cessation rates. Arch Int Med 171:770–777
Lindson N, Aveyard P, Ingram JT, Inglis J, Beach J, West R, Michie S (2009) Rapid reduction versus abrupt quitting for smokers who want to stop soon: a randomised controlled non-inferiority trial. Trials 10:69. doi:10.1186/1745-6215-10-69
Lindson N, Aveyard P (2011) An updated meta-analysis of nicotine preloading for smoking cessation: investigating mediators of the effect. Psychopharmacology 214(3):579–592. doi:10.1007/s00213-010-2069-3
Rose JE, Herskovic JE, Behm FM, Westman EC (2009) Precessation treatment with nicotine patch significantly increases abstinence rates relative to conventional treatment. Nicotine Tob Res 11:1067–1075. doi:10.1093/ntr/ntp103
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010) Personalized smoking cessation: interactions between nicotine dose, dependence and quit success genotype score. Mol Med 16(7–8):247–253. doi:10.2119/molmed.2009.00159
Rose JE (2011) Nicotine preloading: the importance of a pre-cessation reduction in smoking behavior. Psychopharmacology (in press)
Acknowledgments of funding
NL's PhD is funded by the Economic and Social Research Council, through the UK Centre for Tobacco Control Studies (UKCTCS). The UKCTCS gratefully acknowledge funding from British Heart Foundation, Cancer Research UK, Economic and Social Research Council, Medical Research Council, and the Department of Health, under the auspices of the UK Clinical Research Collaboration. PA is part-funded by the UKCTCS and the National Institute of Health Research.
Conflicts of interest
NL has received hospitality from Pfizer Ltd, manufacturers of smoking cessation medication. PA has done consultancy and research on smoking cessation for Pfizer, McNeil, and Celtic Biotechnology.
Author information
Authors and Affiliations
Corresponding author
Electronic supplementary material
Below is the link to the electronic supplementary material.
Online Resource 1
A sub-group analysis comparing the effect of NRT preloading on long-term abstinence in studies where participants reduced their cpd by less than 50% and in studies where participants reduced by more than 50% (DOC 28 kb)
Online Resource 2
A sub-group analysis comparing the effect of NRT preloading on long-term abstinence in studies where continuous abstinence was used as the outcome measure and studies where prolonged or point prevalence abstinence was used as the outcome measure. (DOC 29 kb)
Rights and permissions
About this article
Cite this article
Lindson, N., Aveyard, P. Response to Rose (2011): nicotine preloading: the importance of a pre-cessation reduction in smoking behavior. Psychopharmacology 218, 459–460 (2011). https://doi.org/10.1007/s00213-011-2351-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00213-011-2351-z