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The effect of caffeine on cognitive task performance and motor fatigue

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Abstract

Rationale

In everyday life, people are usually capable of performing two tasks simultaneously. However, in a previous study we showed that during a fatiguing motor task, cognitive performance declined progressively. There is extensive literature on the (positive) effects of caffeine on cognitive and motor performance. These effects are most pronounced under suboptimal conditions, for example during fatigue. However, little is known about the effects of caffeine on cognitive performance during a fatiguing motor task.

Objective

This study was aimed to investigate whether a moderate dose of caffeine could attenuate the decline in cognitive performance during a fatiguing motor task.

Methods

The study consisted of a placebo and a caffeine (3 mg/kg) session. A total of 23 subjects completed these sessions in a semi-randomized and double-blind order. In each session, subjects performed maximal voluntary contractions of the index finger, a choice reaction time (CRT) task and a dual task consisting of a fatiguing motor task concomitantly with the same CRT task. After the fatiguing dual task, the CRT task was repeated.

Results

Caffeine improved cognitive task performance, in both the single and dual task, as shown by decreased reaction times together with unchanged accuracy. Cognitive performance in the dual task deteriorated with increasing fatigue. However, the decrease in cognitive performance in the beginning of the dual task, as observed in the placebo condition, was partly prevented by caffeine administration (i.e., no increase in reaction times). We found no effects of caffeine on motor parameters (absolute force, endurance time or electromyographic amplitude).

Conclusions

Caffeine improved cognitive performance. This effect also extends under demanding situations, as was shown by the performance during the dual task, even during progressive motor fatigue.

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References

  • Behm DG, Whittle J, Button D, Power K (2002) Intermuscle differences in activation. Muscle Nerve 25:236–243

    Google Scholar 

  • Belanger AY, McComas AJ (1981) Extent of motor unit activation during effort. J Appl Physiol 51:1131–1135

    Google Scholar 

  • Bell DG, Jacobs I, Ellerington K (2001) Effect of caffeine and ephedrine ingestion on anaerobic exercise performance. Med Sci Sports Exerc 33:1399–1403

    Google Scholar 

  • Brice CF, Smith AP (2002) Effects of caffeine on mood and performance: a study of realistic consumption. Psychopharmacology 164:188–192

    Article  CAS  Google Scholar 

  • Christopher G, Sutherland D, Smith A (2005) Effects of caffeine in non-withdrawn volunteers. Hum Psychopharmacol Clin Exp 20:47–53

    Google Scholar 

  • Doherty M (1998) The effects of caffeine on the maximal accumulated oxygen deficit and short-term running performance. Int J Sport Nutr 8:95–104

    Google Scholar 

  • Enoka RM, Robinson GA, Kossev AR (1989) Task and fatigue effects on low-threshold motor units in human hand muscle. J Neurophysiol 62:1344–1359

    CAS  PubMed  Google Scholar 

  • Fredholm BB, Battig K, Holmen J, Nehlig A, Zvartau EE (1999) Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev 51:83–133

    CAS  PubMed  Google Scholar 

  • Fuglevand AJ, Zackowski KM, Huey KA, Enoka RM (1993) Impairment of neuromuscular propagation during human fatiguing contractions at submaximal forces. J Physiol 460:549–572

    Google Scholar 

  • Graham TE (2001) Caffeine and exercise: metabolism, endurance and performance. Sports Med 31:785–807

    Google Scholar 

  • Greer F, Friars D, Graham TE (2000) Comparison of caffeine and theophylline ingestion: exercise metabolism and endurance. J Appl Physiol 89:1837–1844

    CAS  PubMed  Google Scholar 

  • Hameleers PA, Van Boxtel MP, Hogervorst E, Riedel WJ, Houx PJ, Buntinx F, Jolles J (2000) Habitual caffeine consumption and its relation to memory, attention, planning capacity and psychomotor performance across multiple age groups. Hum Psychopharmacol 15:573–581

    Google Scholar 

  • Hunter SK, Enoka RM (2001) Sex differences in the fatigability of arm muscles depends on absolute force during isometric contractions. J Appl Physiol 91:2686–2694

    Google Scholar 

  • Jackman M, Wendling P, Friars D, Graham TE (1996) Metabolic catecholamine, and endurance responses to caffeine during intense exercise. J Appl Physiol 81:1658–1663

    Google Scholar 

  • Kalmar JM, Cafarelli E (1999) Effects of caffeine on neuromuscular function. J Appl Physiol 87:801–808

    Google Scholar 

  • Kalmar JM, Cafarelli E (2004) Central fatigue and transcranial magnetic stimulation: effect of caffeine and the confound of peripheral transmission failure. J Neurosci Methods 138:15–26

    Google Scholar 

  • Klapp ST (1995) Motor response programming during sample and choice reaction time: the role of practice. J Exp Psychol 21:1015–1027

    Google Scholar 

  • Lane JD, Phillips-Bute BG (1998) Caffeine deprivation affects vigilance performance and mood. Physiol Behav 65:171–175

    Article  CAS  PubMed  Google Scholar 

  • Lieberman HR, Spring BJ, Garfield GS (1986) The behavioral effects of food constituents: strategies used in studies of amino acids, protein, carbohydrate and caffeine. Nutr Rev 44(Suppl):61–70

    Google Scholar 

  • Lieberman HR, Wurtman RJ, Emde GG, Roberts C, Coviella IL (1987) The effects of low doses of caffeine on human performance and mood. Psychopharmacology 92:308–312

    Article  Google Scholar 

  • Lieberman HR, Tharion WJ, Shukitt-Hale B, Speckman KL, Tulley R (2002) Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea–Air–Land. Psychopharmacology 164:250–261

    Article  Google Scholar 

  • Lopes JM, Aubier M, Jardim J, Aranda JV, Macklem PT (1983) Effect of caffeine on skeletal muscle function before and after fatigue. J Appl Physiol 54:1303–1305

    Google Scholar 

  • Lorist MM, Snel J, Kok A, Mulder G (1994) Influence of caffeine on selective attention in well-rested and fatigued subjects. Psychophysiology 31:525–534

    Google Scholar 

  • Lorist MM, Kernell D, Meijman TF, Zijdewind I (2002) Motor fatigue and cognitive task performance in humans. J Physiol 545:313–319

    Google Scholar 

  • Miller LS, Lombardo TW, Fowler SC (1995) Caffeine and time of day effects on a force discrimination task in humans. Physiol Behav 57:1117–1125

    Google Scholar 

  • Pasman WJ, van Baak MA, Jeukendrup AE, de Haan A (1995) The effect of different dosages of caffeine on endurance performance time. Int J Sports Med 16:225–230

    Google Scholar 

  • Plaskett CJ, Cafarelli E (2001) Caffeine increases endurance and attenuates force sensation during submaximal isometric contractions. J Appl Physiol 91:1535–1544

    Google Scholar 

  • Rabbit P, Banjeri N (1989) How does prolonged practice improve decision speed? J Exp Psychol Gen 118:338–345

    Google Scholar 

  • Rogers PJ, Martin J, Smith C, Heatherley SV, Smit HJ (2003) Absence of reinforcing, mood and psychomotor performance effects of caffeine in habitual non-consumers of caffeine. Psychopharmacology 167:54–62

    CAS  PubMed  Google Scholar 

  • Rohmert W (1960) Determination of the recovery pause for static work of man. Int Z Angew Physiol 18:123–164

    CAS  PubMed  Google Scholar 

  • Ruijter J, Lorist MM, Snel J (1999) The influence of different doses of caffeine on visual task performance. J Psychophysiol 13:37–48

    Google Scholar 

  • Schneider W (1988) Micro experimental laboratory: an integrated system for IBM-PC compatibles. Behav Res Meth Instrum Comput 20:206–217

    Google Scholar 

  • Streufert S, Satish U, Pogash R, Gingrich D, Landis R, Roache J, Severs W (1997) Excess coffee consumption in simulated complex work settings: detriment or facilitation of performance? J Appl Psychol 82:774–782

    Google Scholar 

  • Tarnopolsky M, Cupido C (2000) Caffeine potentiates low frequency skeletal muscle force in habitual and nonhabitual caffeine consumers. J Appl Physiol 89:1719–1724

    Google Scholar 

  • van Duinen H, Lorist MM, Zijdewind I (2003) The effect of caffeine on motor fatigue and cognitive performance in humans. Soc Neurosci Abstr 515.28

  • Warburton DM (1995) Effects of caffeine on cognition and mood without caffeine abstinence. Psychopharmacology 119:66–70

    CAS  PubMed  Google Scholar 

  • Warburton DM, Bersellini E, Sweeney E (2001) An evaluation of a caffeinated taurine drink on mood, memory and information processing in healthy volunteers without caffeine abstinence. Psychopharmacology 158:322–328

    Article  CAS  PubMed  Google Scholar 

  • Wickens CD, Hollands JG (2000) Engineering Psychology and Human Performance. Prentice-Hall, NJ, USA

    Google Scholar 

  • Wilcox RR, Keselman HJ, Muska J, Cribbie R (2000) Repeated measures ANOVA: some new results on comparing trimmed means and means. Br J Math Stat Psychol 53:69–82

    Google Scholar 

  • Williams JH, Barnes WS, Gadberry WL (1987) Influence of caffeine on force and EMG in rested and fatigued muscle. Am J Phys Med 66:169–183

    Google Scholar 

  • Yeomans MR, Ripley T, Davies LH, Rusted JM, Rogers PJ (2002) Effects of caffeine on performance and mood depend on the level of caffeine abstinence. Psychopharmacology 164:241–249

    Article  CAS  Google Scholar 

  • Zijdewind I, Kernell D (1994) Index finger position and force of the human first dorsal interosseus and its ulnar nerve antagonist. J Appl Physiol 77:987–997

    Google Scholar 

Download references

Acknowledgements

This work was supported under the framework of the NWO Cognition Program with financial aid from the Netherlands Organization for Scientific Research (NWO).

The authors would like to thank Dr. Rob Bakels for helpful comments on the manuscript and, Nieske Brouwer and Evelyn Wesseling for the caffeine administration.

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Authors and Affiliations

  1. Department of Medical Physiology, University of Groningen, Groningen, The Netherlands

    Hiske van Duinen, Monicque M. Lorist & Inge Zijdewind

  2. Department of Experimental and Work Psychology, University of Groningen, Groningen, The Netherlands

    Monicque M. Lorist

Authors
  1. Hiske van Duinen
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  2. Monicque M. Lorist
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  3. Inge Zijdewind
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Correspondence to Hiske van Duinen.

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van Duinen, H., Lorist, M.M. & Zijdewind, I. The effect of caffeine on cognitive task performance and motor fatigue. Psychopharmacology 180, 539–547 (2005). https://doi.org/10.1007/s00213-005-2191-9

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  • DOI: https://doi.org/10.1007/s00213-005-2191-9

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