Abstract
Alkaloids are a complex class of biologically active compounds with a broad spectrum of health-related applications. Particularly the alkaloids of indole, steroidal, terpenoids, isoquinoline, and bisbenzylisoquinoline have been extensively investigated. Ultimately, substantial advancement has been highlighted in the investigation of chemical constituents and the therapeutic benefits of plant alkaloids, particularly during the last ten years. A total of 386 alkaloids have been isolated from over 40 families, including Apocynaceae, Annonaceae, Rubiaceae, Menispermaceae, Ranunculaceae, Buxaceae, Papaveraceae, Magnoliaceae, Rutaceae and Phyllanthaceae. This paper will investigate several alkaloids that have been isolated from botanical medicines as well as offer an in-depth analysis of their cytotoxic properties.
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The authors extend their appreciation to the Researchers Supporting Project Number (RSPD2024R620), King Saud University, Riyadh, Saudi Arabia.
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Oladeji, Odelade, Ahmed Mahal, Ahmad J. Obaidullah and Rahadian Zainul wrote the main manuscript text and Oladeji and Ahmed Mahal, prepared the figures. All authors reviewed the manuscript. The authors confirm that no paper mill and artificial intelligence was used.
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Oladeji, O.S., Odelade, K.A., Mahal, A. et al. Systematic appraisals of naturally occurring alkaloids from medicinal plants. Naunyn-Schmiedeberg's Arch Pharmacol (2024). https://doi.org/10.1007/s00210-024-03126-3
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DOI: https://doi.org/10.1007/s00210-024-03126-3